Vaccine against streptococcus suis infection

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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4241841, 4242821, 4241851, 42419711, 424825, A61K 39085, A61K 3900, A61K 39385, A61K 3909

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active

056120427

ABSTRACT:
The present invention relates to a polypeptide of the bacterium Streptococcus suis with a molecular weight of about 54 kD, capable of inducing neutralising antibodies against Streptococcus suis. The invention also relates to a vaccine against Streptococcus suis infection, and a method for the preparation of such a vaccine.

REFERENCES:
patent: 5059419 (1991-10-01), Jacobs
Holt et al. 1990. Protective effect of sera raised against different . . . J. Comp. Path. 103:85-94.
Holt, M.E. et al., "Protective Effect of Sera Raised Against Different Fractions of Streptococcus Suis", Journal of Comparative Pathology, vol. 103, No. 1, Jul. 1990, pp. 85-94
Gottschalk et al., "Production and Characterization of Two Streptococcus Suis Capsular Type 2 Mutants", Veterinary Microbiology, vol. 30, No. 1, Jan., 1992, pp. 59-71.
Vecht, U. et al., "Identification of Two Proteins Associated with Virulence of Streptococcus Suis Type 2", Infection and Immunity, vol. 59, No. 9, Sep., 1991, pp. 3156-3162.
Jacobs et al. 1994. Identification purification and characterization of a Trial . . . Infect. & Immun. 62(5):1742-48.
Gottschalk et al. 1991. Characterization of six new capsular types (23 through 28) . . . J. Clin. Microbiol. 29(11):2590-94.

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