Vaccine against rabies and process for preparation thereof

Details Vaccine against rabies and process for preparation thereof Vaccine against rabies and process for preparation thereof

1994-04-21

2000-02-15

Degen, Nancy

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

4353201, A61K 4800, C12N 1586

Patent

active

060249536

ABSTRACT:
The present invention relates to a vaccinia virus, characterised in that it contains all or part of a DNA sequence (I) coding for an antigenic glycoprotein of rabies.

REFERENCES:
patent: 4393201 (1983-07-01), Curtis
patent: 4722848 (1988-02-01), Paoletti et al.
New Vaccine and Initiative Mean End of Rabies in Sight for Europe?, Nature, vol. 336, 1 Dec.
The Wistar Institute Announces New Recombinant Rabies Vaccine Trials in Western Europe, Plans for U.S. Trials, Wistar News Release, May 3, 1988, The Wistar Institute.
Rabies Vaccine Ready for Testing, International Herald Tribune, Thursday, May 19, 198.
U.S. Test Sought of Vaccine, News/Sun-Sentinel, Thursday, May 5, 1988.
Recombinant DNA Research and Wildlife Studies Focus on Reducing the Spread of Rabies, Research Resources Report, vol. X, No. 4, Apr. 1986.
Verma (1977), Biochim. Biophys. Acta 473: 1-38.
Paoletti et al, Proc. Natl. Acad. Sci. USA, vol. 81, pp. 193-197 (1984).
Panicali et al, Proc. Natl. Acad. Sci USA, vol. 80, pp. 5364-5368, (1983).
Smith et al, Proc. Natl. Acad Sci USA, vol. 80, pp. 7155-7159, (1983).
Dietzschold et al, Journal of Virology, vol. 44, pp. 595-602, (1982).
Nature, vol. 312, Nov. 8, 1984, M.P.Kieny et al: "Expression of rabies virus glycoprotein from a recombinant vaccinia virus", pp. 163-166, see the whole article.
Proceedings of the National Academy of Sciences, vol. 81, Nov. 1984 (US) T.J.Wiktor et al: "Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene", pp. 7194-7198, see the whole article.

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