Vaccine against lyme disease

Details Vaccine against lyme disease Vaccine against lyme disease

1986-08-14

1988-01-26

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 88, 435240, A61K 3902

Patent

active

047216174

ABSTRACT:
A vaccine for the immunization of mammals against Lyme borreliosis (Lyme disease) is disclosed which contains an effective amount of inactivated Borrelia burgdorferi spirochetes dispersed in a physiologically-acceptable, non-toxic liquid vehicle.

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patent: 4596707 (1986-06-01), Ristic et al.
Nature, 280, Aug. 1979, 491-493, Allen et al.
Lyme Disease, pub. by Pfizer Central Research (1986).
Steere et al., N. Engl. J. Med., 1983; 308: 733-40.
Barbour, A. G., Yale J. Biol. Med., 1984: 57: 521-525.
Johnson et al., 2nd International Symp. on Lyme Disease and Related Disorders, Sep. 17-19, 1985, abstract.

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