Vaccine against hepatitis A virus

Details Vaccine against hepatitis A virus Vaccine against hepatitis A virus

1988-07-12

1990-01-16

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Lymphokine

514894, A61K 3929

Patent

active

048942286

ABSTRACT:
The present invention provides an attenuated hepatitis A virus useful as a vaccine.

REFERENCES:
patent: 4164566 (1979-08-01), Provost et al.
patent: 4620978 (1986-11-01), Daemer et al.
Feinstone, S. M., Daemer, R. J., Gust, I. D., Purcell, R. H., Live Attenuated Vaccine for Hepatitis A, Dev. Biol. Stand., 1983; 54: 429-432.
Provost, P. J., Conti, P. A., Giesa, P. A. et al., Studies in Chimpanzees of Live, Attenuated Hepatitis A Vaccine Candidates, Proc. Soc. Exp. Biol. Med., 1983; 172: 357-363.
Ticehurst, J. R., Racaniello, V. R., Baroudy, B. M., Baltimore, D., Purcell, R. H., Feinstone, S. M., Molecular Cloning and Characterization of Hepatitis A Virus cDNA, Proc. Natl. Acad. Sci. USA, 1983; 80: 5885-5889.
von der Helm, K., Winnacker, E. L., Deinhardt, F. et al., Cloning of Hepatitis A Virus Genome, J. Virol. Methods, 1981; 3: 37-43.
Daemer et al., Infection and Immunity, 32(1): 388-393, Apr. 1981.
Purcell et al., "Hepatitis A Virus" (in press).

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