Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Reexamination Certificate
2006-04-11
2006-04-11
Devi, S. (Department: 1645)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
C424S137100, C424S130100, C424S164100, C424S163100, C424S169100, C424S170100, C424S257100, C424S250100
Reexamination Certificate
active
07025963
ABSTRACT:
A vaccine, effective in inducing the production of antibodies with which to immunize a second subject passively against infection by Gram-negative bacteria and LPS-mediated pathology, comprises a non-covalent polyvalent complex formed between purified, detoxified LPS derived fromE. coliand purified outer membrane protein derived fromN. meningitidis. The same vaccine will also actively immunize a host subject against Gram-negative bacterial infections and LPS-mediated pathology. Meningococcal infections are included among those Gram-negative bacterial infections protected against by the vaccine.
REFERENCES:
patent: 4707543 (1987-11-01), Zollinger et al.
patent: 4912094 (1990-03-01), Myers et al.
patent: 4929604 (1990-05-01), Munford et al.
patent: WO 91/01755 (1991-02-01), None
Ziegler et al. New England Journal of Medicine 307(20):1225-1230, 1982.
Teng et al. PNAS 82: 1790-1794, abstract, 1985.
Wickstrom et al. Vet. Microbiol. 13: 259-271, abstract, 1987.
Jachymek W. Postepy Hig Med. Dosw. 49: 171-178, abstract, 1995.
Tomita et al. J. Dairy Sci. 76: Suppl. 1: 9. 159, abstract, 1993.
Spier et al. Circ. Shock. 28: 235-248, abstract, 1989.
Ziegler et al. Clin. Res. 29: p. 576A, abstract, 1981.
Yoshioka et al. Res. Commun. Chem. Pathol. Pharmacol. 80: 367-370, abstract, 1993.
Tyler et al. Am. J. Vet. Res. 55: 1256-1260, abstract, 1994.
Tyler et al. J. Dairy Sci. 74: 1235-1242, 1991.
Tyler et al. J. Immunol. Methods 129: 221-226, 1990.
Tyler et al. Am. J. Vet. Res. 49: 1950-1954, 1988.
Ding et al. J. Med. Microbiol. 31: 95-102, 1990.
Nixdorff et al. In: Microbial Infections. (Eds) H. Friedman et al. Plenum Press, New York, 49-61, 1992.
Young et al. J. Clin. Invest. 56: 850-861, 1975.
Ziegler et al. In: Seminars in Infectious Disease. (Eds) Weinstein et al. vol. IV, 366-369, 1982.
Liu et al. PNAS 89: 4633-4637, 1992.
Marks et al. J. Clin. Invest. 69: 742-749, 1982.
Cryz Jr. et al. Eur. J. Clin. Microbiol. 4: 180-185, 1985.
Moreno et al. Infect. Immun. 47: 527-533, 1985.
Cohen et al. Lancet 1: 8-11, 1987.
Hawe et al. In: Abstracts of papers presented in the Meeting on Modern Approaches to New Vaccines, Cold Spring Harbor Labortory, Sep. 16-20, 1992.
Lugowski et al. J. Immunol. Methods 95: 187-194, 1986.
Tyler et al. J. Dairy Sci. 75: 1821-1825, 1992.
Tomita GM. Immunization of dairy cows against coliform mastitis. Dissertation, The Ohio State University, 1985.
Tyler et al. J. Vet. Intern. Med. 4: 17-25, 1990.
McCullus et al. Infect. Immun. 55: 1042-1046, abstract, 1985.
Bhattacharjee et al. Infect. Dis. Clin. North Amer. 13: 355-369, Jun., 1999.
Schwartzer et al. J. Infect. Dis. 158: 1135-1136, 1985.
Davis et al. J. Exp. Med. 147: 1007-1017, abstract, 1978.
McCabe et al. Progr. Clin. Biol. Res. 47: 107-117, 1980.
Salles et al. J. Infect. Dis. 159: 641-647, abstract, 1989.
Nelles et al. Infect. Immun. 46: 677-681, 1985.
Tomita et al. J. Dairy Sci. 78: 2745-2752, 1995.
Ziegler et al. J. Infect. Dis. 158: 286-29, 1988.
Moore et al. Transplanation 44: 249-253, 1987.
Dunn et al. Surgery 96: 440-446, 1984.
Dale et al. J. Infect. Dis. 166: 316-325, 1992.
Fenwick et al. Infect. Immun. 53: 298-304, 1987.
Fenwick et al. Am. J. Vet. Res. 47: 1888-1891, 1987.
Priest et al. Surgery 106: 147-154, 1989.
Pollack et al. J. Clin. Invest. 72: 1874-1881, 1983.
Gupta et al. In: Abstracts of the Annual Meeting of the American Society for Microbiology, May, 13-17, Anaheim, California, E-5, 1990.
Alan S. Cross. Editorial. Annals of Internal Medicine 121 (1): 58-60, Jul. 1, 1994.
Bhattacharjee “Complex Vaccine With Neisseria..”,94th ASM General Meeting, , pp. 151, May 1994.
Cross et al. “Therapeutic Intervention In Sepsis . . . ”,Journal Endotoxin Research, pp. 57-69, 1994.
Bhattacharjee “Affinity PurifiedE. coli . . . ”, Clinical Research, 41:2, 1993.
Cross et al. “The Efficacy of Combination . . . ”,Journal Infectious Diseases, 167:112-8, Jan. 1993.
Greenman et al. “E5 Antibody in Gram-Negative Sepsis . . . ”,JAMA, 266:8, pp. 1097-1102, Aug. 1991.
Ziegler et al. “Treatment Gram-Negative Bacteremia . . . ”,New Eng. J. of Med., 324:7, pp. 429-436, Feb. 1991.
Cryz, Jr. et al. “Synthesis, Character.Escherichia coli018 . . . ”,Infect. Immun., 58:2, pp. 373-377, Feb. 1990.
Cryz, Jr. et al. “Pseudomonas O-Antigen-Toxin A Vaccine . . . ”,Prevent. P. Aeruginosa Infect., 42:177-83, 1989.
Calendra et al. “Immunotherapy for Gram-Negative Septic Shock . . . ”,J. Infect. Dis., 158:2, pp. 312-319, Aug. 1988.
Kanegasaki et al. “Comparison Biological Activities . . . ”,Bact. Endo. Chem., PP. 149-58, 1984.
Ziegler et al. “Treatment Gram-Negative Bacteremia . . . ”,New Eng. J. Med., 307:1225-1230, Nov. 1982.
Ziegler et al. “Prevention Lethal Pseudomonas . . . ”,Trans. Am. Physiol., 88:101-08, 1975.
Ziegler et al. “Treatment ofE. coli& Klebsiella Bacteremis . . . ”,J. Immun., 112:2, pp. 433-438, Aug. 1973.
Bhattacharjee Apurba
Cross Alan
Sadoff Jerald
Zollinger Wendell
Arwine Elizabeth
Devi S.
Harris Charles H.
Moran John Francis
United States of America as represented by the Secretary of the
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