Vaccine against Gram-negative bacterial infections

Details Vaccine against Gram-negative bacterial infections Vaccine against Gram-negative bacterial infections

2006-03-28

2006-03-28

Devi, S. (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

C424S234100, C424S184100, C424S241100, C424S250100, C424S257100, C424S259100, C424S260100, C514S023000, C536S123100, C530S350000, C530S825000, C530S806000

Reexamination Certificate

active

07018636

ABSTRACT:
A vaccine, effective in inducing the production of antibodies with which to immunize a second subject passively against infection by Gram-negative bacteria and LPS-mediated pathology, comprises a non-covalent polyvalent complex formed between purified, detoxified LPS derived fromE. coliand purified outer membrane protein derived fromN. meningitidis. The same vaccine will also actively immunize a host subject against Gram-negative bacterial infections and LPS-mediated pathology. Meningococcal infections are included among those Gram-negative bacterial infections protected against by the vaccine.

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