Vaccine against equine herpesvirus type 1

Details Vaccine against equine herpesvirus type 1 Vaccine against equine herpesvirus type 1

1995-06-06

1998-08-18

Huff, Sheela

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

4241471, 4241591, 435339, A61K 39395

Patent

active

057955786

ABSTRACT:
The present invention is directed to a gene encoding an envelope glycoprotein of equine herpesvirus type 1 (EHV-1), the glycoprotein D (gD) gene, its gene product and antibodies directed against gD polypeptides. The envelope glycoproteins of herpesvirus are major targets of the inmune response to herpesviral infection. Hence, an important aspect of this invention is directed towards a vaccine against EHV-1 and treatment of EHV-1 infection by anti-EHV-gD antibodies or antisera.

REFERENCES:
Stokes et al J Gen Virol vol. 70:1173-1183, 1989.
Allen et al J Virology vol. 61 No. 8:2454-2461, 1987.
Whittaker et al J Gen Virol vol. 73: 801-809, 1992.

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