Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from panax or acanthopanax
Reexamination Certificate
2005-06-14
2005-06-14
Leith, Patricia (Department: 1654)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
Containing or obtained from panax or acanthopanax
C424S725000, C424S278100, C424S690000
Reexamination Certificate
active
06905712
ABSTRACT:
A composition, which includes ingredients capable of enhancing the immunogenic effect of a vaccine, includes an aluminium salt and at least one ginsenoside, such as a tri-terpenoid glycoside, preferably a tri-terpenoid glycoside of the structure of Rb1. In one particular embodiment, the aluminium salt is Al(OH)3. A kit for use as adjuvant or co-adjuvant of an immunogenic composition includes the composition. The use of such a tri-terpenoid glycoside in the manufacture of a pharmaceutical preparation enhanced the immunogenic effect of a vaccine. A pharmaceutical preparation includes the composition and an aluminium salt, such as Al(OH)3 and a pharmaceutically acceptable carrier.
REFERENCES:
patent: 5817314 (1998-10-01), So et al.
patent: 6083512 (2000-07-01), Roberts
patent: WO 96/33739 (1996-10-01), None
patent: WO 98/15287 (1998-04-01), None
J. Y. Ro et al., “A single component of ginsenosides extracted from Korean Red Ginseng Radix has an adjuvant activity”, West-Pac Allergy Symp. Korean-Jpn. Jt. Allergy Symp., 5th, 7th, 171-175. 1997. American Chemical Society abstract.
Leith Patricia
Statens Veterinarmedicinska Anstalt
Young & Thompson
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