Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1982-02-25
1984-08-21
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Lymphokine
424 88, 424 92, A61K 3902, A61K 3912, A61K 39145, A61K 39245
Patent
active
044669577
ABSTRACT:
There are disclosed mammalian vaccine compositions comprising an inactivated whole or subunit vaccine or toxoid and an adjuvant having the formula ##STR1## wherein R is hydrogen or lower alkyl, R.sub.1 is hydrogen, lower alkyl, lower alkoxy, trifluoromethyl or halo, R.sub.2 is hydrogen, chloro or nitro, n is 1 or 2 and pharmaceutically acceptable salts thereof.
REFERENCES:
patent: 3704239 (1972-11-01), Wei et al.
patent: 4158052 (1979-06-01), Audibert et al.
patent: 4214089 (1980-07-01), Fenichel et al.
Chemical Abstracts, vol. 94, No. 1, Abstract No. 4018a, 1981.
Chemical Abstracts, vol. 95, No. 1, Abstract No. 411w, 1981.
Chem. Abstr. 97: 84596n, (1982), of Michiels, Metal Methods Enzymol, (1982), 84, (Immunochem. Tech., Part 1), :542-551, Radio-Immunoassay of Dimozide.
Chem. Abstr. 94: 4018a, (1981), of Al Burn et al., U.S. Pat. 4,214,089, 22 Jul. 1980, Thiazolo[3,2-a]benzimidazoles etc . . . as . . . Enhancers of the Immune Response.
Chem. Abstr. 92: 33954s, (1980), of Warren, G. et al., Immunopharmacology, 1979, 1, (4), :269-276, Stimulation by a Hydroxythiazolo Benzimidazole of Enhanced Formation of Antibodies to Sheep Erythrocytes in Vitro and in Vivo.
Chem. Abstr. 89: 141183m, (1978), Warren et al., Experientia, (1978), 34, (6), :802-3, Immunomodulating Effects of a Hydroxythiazolo Benzimidazole.
Chem. Abstr. 89: 53363q, 1978, of Eur. J. Cancer, 1978, 144, 393-400, The Immunostimulatory Activity of 3-(p-chlorophenyl)-2,3-dihydro-3-hydroxythiazole[3,2-a]benzimidazole-2-ace tic Acid.
Chem. Abstr. 87: 143863m, 1977, of Cancer Res, 1977, 37, (9), :3338-43, Association of Macrophase Activation with Antitumor Activity by Synthetic and Biological Agents . . . Adjuvants . . . Wy. 13876 . . . Typhoid Vaccine".
Chem. Abstr. 83: 37403y, 1975, of Michiels Life Science, 1975, 16, (6), 937-944, Radio Immunoassay of the Neuroleptic Drug Dimozide.
Grant Norman H.
Hjorth Richard N.
Moore Bobby O.
American Home Products Corporation
Rose Shep K.
Tarnowski George
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