Vaccine adjuvant comprising interleukin-15

Details Vaccine adjuvant comprising interleukin-15 Vaccine adjuvant comprising interleukin-15

1995-07-19

1998-05-05

Ulm, John

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

514 2, 514 8, 514 12, 514885, 4242781, 530351, A61K 3820

Patent

active

057470243

ABSTRACT:
Methods of enhancing a mammal's immune response to a vaccine antigen are disclosed. Interleukin-15 can be used as a vaccine adjuvant to enhance or potentiate the immune response to a vaccine. Compositions comprising an immunogenic amount of vaccine antigen and an immunogenicity-augmenting amount of IL-15 are also provided by the invention. IL-15 can be used alone in the invention or in concurrent or sequential combination with additional vaccine adjuvants.

REFERENCES:
Cohen Jon (1995) Science vol. 270 p. 908.

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