Vaccine

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

Reexamination Certificate

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C424S190100, C424S199100, C424S232100, C424S272100, C424S093300, C424S184100, C435S456000, C435S069300, C435S320100, C435S455000

Reexamination Certificate

active

10856118

ABSTRACT:
The present invention relates to a fowlpox virus genome which has modifications in one or more wild-type FPV genes. The present invention also relates to a viral particle comprising such a genome and its use to deliver a nucleotide of interest (NOI) to a target cell. The present invention also relates to vaccination methods, particularly a method which comprises administering a priming composition (which comprises a first non-replicating viral vector) and a boosting composition (which comprises a second non-replicating viral vector) to a subject to treat and/or prevent a disease.

REFERENCES:
patent: 4053582 (1977-10-01), Stickl
patent: 4748019 (1988-05-01), Lysons
patent: 5110587 (1992-05-01), Paoletti et al.
patent: 5185146 (1993-02-01), Altenburger
patent: 5225336 (1993-07-01), Paoletti
patent: 5453364 (1995-09-01), Paoletti
patent: 5462734 (1995-10-01), Letchworth, III et al.
patent: 5766597 (1998-06-01), Paoletti et al.
patent: 5846546 (1998-12-01), Hurwitz et al.
patent: 6103244 (2000-08-01), Dorner et al.
patent: 6663871 (2003-12-01), McMichael et al.
patent: 2003/0138454 (2003-07-01), Hill et al.
patent: 2004/0018177 (2004-01-01), Hill et al.
patent: 2004/0131594 (2004-07-01), McMichael et al.
patent: 2004/0175365 (2004-09-01), McMichael et al.
patent: 2004/0191272 (2004-09-01), McMichael et al.
patent: 2004/0197349 (2004-10-01), McMichael et al.
patent: 2004/0213799 (2004-10-01), McMichael et al.
patent: 2005/0175627 (2005-08-01), Schneider
patent: 0 638 316 (1995-02-01), None
patent: 0 753 581 (1997-01-01), None
patent: 0517292 (2000-02-01), None
patent: WO92/22641 (1992-12-01), None
patent: WO93/03145 (1993-02-01), None
patent: WO96/26271 (1996-08-01), None
patent: WO97/39771 (1997-10-01), None
patent: WO98/04728 (1998-02-01), None
patent: WO98/56919 (1998-12-01), None
patent: WO9856919 (1998-12-01), None
patent: WO 01/02607 (2001-01-01), None
patent: WO 01/14416 (2001-03-01), None
patent: WO 01/85932 (2001-11-01), None
patent: WO 01/85932 (2001-11-01), None
patent: WO 02/068654 (2002-09-01), None
patent: WO 02/068654 (2002-09-01), None
patent: WO 2005/030964 (2005-04-01), None
Laidlaw, S.M. et al., “Comparison of the genome sequence of FP9, and attenuated, tissue culture-adapted European strain of Fowlpox virus, with those of virulent American and European viruses”, 2004, J. Gen. Virol., vol. 85: pp. 305-322.
Schneider, J. et al., “Induction of CD8+ T cells using heterologous prime-boost immunisation strategies”, 1999, Immunological Rev., vol. 170: pp. 29-38.
Skinner, M.A. et al., “Fowlpox virus as a recombinant vaccine vector for use in mammals and poultry”, 2005, Expert Rev. Vaccines, vol. 4: pp. 63-76.
Carvalho, L.J.M. et al., “Malaria Vaccine: Candidate Antigens, Mechanisms, Constraints and Prospects”, 2002, Scand. J. Immunol., vol. 56: pp. 327-343.
Carter, B., “Gene Therapy as Drug Development”, 2000, Mol. Therapy, vol. 1: pp. 211-212.
Holder, A. et al., “Faliciparum Malaria MSP1 Workshop Progress toward MSP1 Vaccine Development and Testing”, 2000, Malaria Vaccine Initiative, pp. 1-30.
Niewiesk, S. et al., “Measles Virus-Induced Immune Suppression in the Cotton Rat (Sigmodon hispidus) Model Depends on Viral Glycoproteins”, 1997, J. Virol., vol. 71: pp. 7214-7219.
Afonso, et al., NCBI Accession No. AF198100,J. Virology 74(8):3815-3831 (2000).
Anderson, et al., “Enhanced CD8 T Cell Response and Protective Efficacy Against Malaria Using Recombinant Fowlpox Virus In Heterologous Prime/Boost Immunisation Regimes,” Abstract,Immunology 101(Supplement 1):32 (2000).
Hodge, James W., et al., “Diversified Prime and Boost Protocols Using Recombinant Vaccinia Virus and Recombinant Non-Replicating Avian Pox Virus to Enhance T-Cell Immunity and Antitumor Responses,”Vaccine 15(6-7):759-768 (1997).
Tsukamoto, Kenji, et al., “Dual-Viral Vector Approach Induced Strong and Long-Lasting Protective Immunity Against Very Virulent Infectious Bursal Disease Virus,”Virology 269(2):257-267 (2000).
Irvine, K.R., et al., “Enhancing Efficacy of Recombinant Anticancer Vaccines with Prime/Boost Regiments That Use Two Different Vectors,”J. Natl. Cancer Institute 89(21):1595-1601 (1997).
Taylor, J. And Paoletti, E., “Fowlpox Virus As A Vector in Non-Avian Species,”Vaccine 6:466-468 (1988).
Taylor, J., et al., “Recombinant Fowlpox Virus Inducing Protective Immunity in Non-Avian Species,”Vaccine 6(6):497-503 (1988).
Afonso, C.L., et al., “The Genome of Fowlpox Virus,”J. Virology 74(8):3815-3831 (2000).
Shaw, I., and Davison, T.F., “Protection From IBDV-Induced Bursal Damage By A Recombinant Fowlpox Vaccine, fplBD1, Is Dependent ON the Titre of Challenge Virus and Chicken Genotype,”Vaccine18:3230-3241 (2000).
Boulanger, D., et al., “The 131-Amino-Acid Repeat Region of the Essential 39-Kilodalton Core Protein of Fowlpox Virus FP9, Equivilant to Vaccinia Virus A4L Protein, Is Nonessential and Highly Immunogenic,”J. Virol 72(1):170-179 (1998).
Boulanger, D., et al., “Morphogenesis and Release of Fowlpox Virus,”J. of Gen. Virol. 81:675-687 (2000).
Laidlaw, S. M., et al., “Fowlpox Virus Encodes Nonessential Homologs of Cellular Alpha-SNAP, PC-1, and an Orphan Human Homolog of a Secreted Nematode Protein,”J. Virol. 72(8):6742-6751 (1998).
Dale, C. J., et al., “Induction of HIV-1-Specific T-Helper Responses and Type 1 Cytokine Secretion Following Therapeutic Vaccination of Macaques with A Recombinant Fowlpoxvirus Co-expressing Interferon-Gamma,”J. Med. Primatol. 29:240-247 (2000).
Kent, S. J., et al., “Enhanced T-Cell Immunogenicity and Protective Efficacy of a Human Immunodeficiency Virus Type 1 Vaccine Regimen Consisting of Consecutive Priming with DNA and Boosting with Recombinant Fowlpox Virus,”J. Virol. 72(12):10180-10188 (1998).
Boursnell, M. E. G., et al., “a Fowlpox Virus Vaccine Vector with Insertion Sites in the Terminal Repeats: Demonstration of its Efficacy Using the Fusion Gene of Newcastle Disease Virus,”Veterin. Microbiology 23:305-316 (1990).
Boursnell, M. E. G., et al., “Insertion of the Fusion Gene from Newcastle Disease Virus into a Non-essential Region in the Terminal Repeats of Fowlpox Virus and Demonstration of Protective Immunity Induced by the Recombinant,”J. Gen. Virology 71:621-628 (1990).
Boyle, D. B. And Heine, H. G., “Recombinant Fowlpox Virus Vaccines for Poultry,”Immunol and Cell Biol. 71:391-397 (1993).
Boyle, D. B., et al., “Comparison of Field and Vaccine Strains of Australian Folwpox Viruses,”Arch Virol 142:737-748 (1997).
Brooks, J. V., et al., “Boosting Vaccine for Tuberculosis,”Infection and Immunity 69(4): 2714-2717 (2001).
Campbell, J. I. A., et al., “Tandem Repeated Sequences Within the Terminal Region of the Fowlpox Virus Genome,”J. Gen. Virol. 70:145-154 (1989).
Grosenbach, D. W., et al., “Synergy of Vaccine Strategies to Amplify Antigen-specific Immune Responses and Antitumor Effects,”Cancer Res 61:4497-4505 (2001).
Hertig, C., et al., “Field and Vaccine Strains of Fowlpox Virus Carry Integrated Sequences from the Avian Retrovirus, Reticuloendotheliosis Virus,”Virol. 235:367-376 (1997).
Irvine, K. R., et al., “Route of Immunization and the Therapeutic Impact of Recombinant Anticancer Vaccines,”J. of the Natl. Cancer Inst. 89(5):390-392 (1997).
Kent, S. J., et al., A Recombinant Avipoxvirus HIV-1 Vaccine Expressing Interferon-gamma is Safe and Immunogenic in Macaques,Vaccine 18:2250-2256 (1999).
Gilbert, S. C., et al., “A Protein Particle Vaccine Containing Multiple Malaria Epitopes,”Nature Biotechnology 15:1280-1284 (1997).
Mahnel, et al., “Experiences with Immunization Against Orthopox Viruses of Humans and Animals Using Vaccine Strains MVA,”Berliner Und Munchener Tierarztliche Wochenschrift 107(8):253-256 (1994) Abstract Only.
Meyer

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