V-like domain binding molecules and polynucleotides encoding...

Details V-like domain binding molecules and polynucleotides encoding... V-like domain binding molecules and polynucleotides encoding...

2008-07-29

2008-07-29

Ouspenski, Ilia (Department: 1644)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S320100, C435S252300, C435S069100

Reexamination Certificate

active

07405288

ABSTRACT:
The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterised in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.

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