Utilization of 3-methyl-2-oxo-ethyl-pentanoate as a perfuming in

Perfume compositions – Perfume compositions – Oxygen containing active ingredient

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512 1, 512 26, 512 27, 424401, A61K 746, A61K 700

Patent

active

059522925

ABSTRACT:
3-Methyl-2-oxo-ethylpentanoate or an isomer thereof are very useful compounds in the field of perfumery, having an unusual, fruity odor note that can be described as a fresh walnut odor together with a rum type note.

REFERENCES:
R. Kozlowski et al., "Lower Aliphatic 2-Oxoacids and their Ethyl Esters From Ethyl Esters of 2-Hydroxy Acids", Organic Preparations and Procedures Inc. 21(1), 75-82 (1989).
Y. Akiyama et al., "Studies on Conjugated Nitriles. IV.", Chem. Pharm. Bull. 32 (5) 1800-1807 (1984).
Y. Akiyama et al., "Reaction of Organocadmium Reagents with Ethyl Cyanoformate: preparation of .alpha.-Keto Ester", Chemistry Letters, pp. 1231-1232, 1983.
P. Yates et al., "Synthesis of piperazine-2,5-diones related to piperzaine-2,5-dione, 2. Route via cyclic intermediates". Can. J. Chem. 61970, 1397-1404 (1983).
H.M. Walborsky, "Partial Asymmetric Syntheses of Amino Acids Using Lithium Aldimine Precursors", J. Org. Chem., vol. 39, (5), 604-607, 1974.
L.N. Akimova. "Preparation of Estes of .alpha.-Keto Acids by the Actions of Grignard Reagents of Oxalic Esters". Zhurnal Organicheskoi Khimii 5(9) pp. 1569-1571, Sep. 1969.

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