Uterine cervical cancer computer-aided-diagnosis (CAD)

Image analysis – Applications – Biomedical applications

Reexamination Certificate

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Details

C128S841000, C424S430000

Reexamination Certificate

active

07664300

ABSTRACT:
Uterine cervical cancer Computer-Aided-Diagnosis (CAD) according to this invention consists of a core processing system that automatically analyses data acquired from the uterine cervix and provides tissue and patient diagnosis, as well as adequacy of the examination. The data can include, but is not limited to, color still images or video, reflectance and fluorescence multi-spectral or hyper-spectral imagery, coherent optical tomography imagery, and impedance measurements, taken with and without the use of contrast agents like 3-5% acetic acid, Lugol's iodine, or 5-aminolevulinic acid. The core processing system is based on an open, modular, and feature-based architecture, designed for multi-data, multi-sensor, and multi-feature fusion. The core processing system can be embedded in different CAD system realizations. For example: A CAD system for cervical cancer screening could in a very simple version consist of a hand-held device that only acquires one digital RGB image of the uterine cervix after application of 3-5% acetic acid and provides automatically a patient diagnosis. A CAD system used as a colposcopy adjunct could provide all functions that are related to colposcopy and that can be provided by a computer, from automation of the clinical workflow to automated patient diagnosis and treatment recommendation.

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Ferris, Daron G.; Cox, J. Thomas; O'Connor, Dennis M.; Wright, V. Cecil and Foerster, John, Modem Colposcopy Textbook and Atlas, Chapter 8, Normal and Abnormal Colposcopic Features, Kendall/Hunt Publishing Company, Iowa 2004, pp. 175-191.
Sellors, John W. and Sankaranarayanan, R., Colposcopy and Treatment of Cervical Intraepithelial Neoplasia: A Beginners' Manual, Chapter 1, An introduction to the anatomy of the uterine cervix, International Agency for Research on Cancer, Lyon, France 2003, pp. 1-12.
Apgar, Barbara S, Brotzman, Gregory L., Spitzer, Mark, Colposcopy Principles and Practice An Integrated Textbook and Atlas, Chapter 6, Normal Transformation Zone, W.B. Saunders Company, Pennsylvania 2002, pp. 147-158.

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