Uses of triplex forming oligonucleotides for the treatment of hu

Details Uses of triplex forming oligonucleotides for the treatment of hu Uses of triplex forming oligonucleotides for the treatment of hu

1994-06-06

1997-07-22

Rories, Charles C. P.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

435 6, 435 723, 514 44, 536 245, 536 2431, 536 2432, 536 2433, C12N 510, C07H 2104, C12Q 168, G01N 33574

Patent

active

056503164

ABSTRACT:
The present invention provides novel methods of treating anti-neoplastic and non-neoplastic cell proliferative diseases. The present methods involve administration of triplex forming oligonucleotides to humans to inhibit the biological activity of tumor necrosis factor. Also provided are methods of treating neuro-oncologic states and renal cancer.

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