Uses of neuraminidase inhibitors in infectious diseases

Details Uses of neuraminidase inhibitors in infectious diseases Uses of neuraminidase inhibitors in infectious diseases

2011-03-22

2011-03-22

Fetterolf, Brandon J (Department: 1628)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S043000, C514S471000

Reexamination Certificate

active

07910620

ABSTRACT:
The present invention relates to methods of decreasing the infectivity, morbidity and rate of mortality, in treating diseases associated with a variety of pathogenic organisms, specifically diseases involving one or more pathogens that require neuraminidase as a virulence factor. In addition, the present invention uses biology based therapy to treat neuraminidase dependent infections or diseases dependent on sialic acid metabolism.

REFERENCES:
patent: 2004/0053858 (2004-03-01), Berg
patent: 2004/0248825 (2004-12-01), McCullers
Elliott, Michael. “Zanamivir: from drug design to the clinic”. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2001. vol. 356. pp. 1885-1893.
He et al. “Clinical Pharmacokinetics of the Prodrug Oseltamivir and its Active Metabolite Ro 64-0802”. Clinical Pharmacokinetics. 1999. vol. 37, No. 6. pp. 471-484.
McCullers et al. “Role of Neuraminidase in Lethal Synergism between Influenza Virus and Streptococcus pneumoniae”. The Journal of Infectious Diseases. 2003. vol. 187. pp. 1000-1009.
Young et al. “RWJ-270201 (BCX-1812): a novel neuraminidase inhibitor for influenza”. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2001. vol. 356. pp. 1905-1913.
Nappert et al. “Determination of serum organic acids in puppies with naturally acquired parvoviral enteritis”. The Canadian Journal of Veterinary Research. 2002. vol. 66. pp. 15-18.
Stein, Expert Opinion on Investigational Drugs (2005) 14:107-109.
Neill et. al., Expert Opinion on Investigational Drugs (2004) 13:1045-1063.
Useh et. al., Veterinary Quarterly (2003) 25:155-159.
Macintyre, D. (Feb. 2004, Management of Severe Parvoviral Enteritis. Presented at the Western Veterinary Conference, Las Vegas NV).
Useh et. al. (Veterinary Quarterly (2003) 25:155-159).
Elliot (Phil. Trans. R. Soc. Lond. B (2001) 356:1885-1893).
Goodman and Gilman's The Pharmacological Basis of Therapeutics (Tenth Edition (2001), McGraw Hill, Chapter I, pp. 3-29).

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