Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.
Reexamination Certificate
2007-02-27
2007-02-27
Weber, Jon (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Scleroproteins, e.g., fibroin, elastin, silk, etc.
C530S387100, C514S021800
Reexamination Certificate
active
10393193
ABSTRACT:
The present invention provides a method of recovering cellular functions in cells following injury, comprising the step of contacting said cells with collagen IV or a natural or mutated fragment thereof. Further provided is a pharmaceutical composition, comprising a therapeutically effective amount of collagen IV or a natural or mutated fragment thereof and a topically acceptable carrier.
REFERENCES:
Nowak et al., Toxicology and Applied Pharmacology, vol. 167, pp. 37-45, 2000.
Hudson et al., The Journal of Biological Chemistry, vol. 268, No. 35, pp. 26033-26036, Dec. 15, 1993.
Kalluri et al., The Journal of Biological Chemistry, vol. 275, No. 17, pp. 12719-12724, Apr. 28, 2000.
Houglum et al., Am. J. Clin. Nutr., vol. 54, pp. 1141S-1143S, 1991.
Nony Paul A.
Schnellmann Ricky Gene
Adles Benjamin Aaron
Mohamed Abdel A.
The University of Arkansas for Medical Sciences
Weber Jon
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