Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Reexamination Certificate
2003-04-15
2008-08-19
Mondesi, Robert B. (Department: 1656)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
C435S007600, C435S007900, C435S007100, C435S069100, C436S512000, C424S009100, C424S094100
Reexamination Certificate
active
07413850
ABSTRACT:
Use of carbamoyl phosphate synthetase 1 (CPS 1) and/or of fragments of the N-terminal part of CPS 1 from body fluids or body tissues as marker peptides for the diagnosis and for the prognosis and the monitoring of inflammations and infections, including sepsis, and of liver failure as part of multiorgan failure or for determinations in connection with inflammatory and other liver diseases.
REFERENCES:
patent: 4822733 (1989-04-01), Morrison
patent: 5512493 (1996-04-01), Mathis et al.
patent: 5639617 (1997-06-01), Bohuon
patent: 7132246 (2006-11-01), Bergmann et al.
patent: 7157081 (2007-01-01), Bergmann et al.
patent: 2004/0180396 (2004-09-01), Bergmann et al.
patent: 2005/0059104 (2005-03-01), Bergmann et al.
patent: 2005/0064506 (2005-03-01), Bergmann et al.
patent: 2005/0074811 (2005-04-01), Bergmann et al.
patent: 2005/0106645 (2005-05-01), Bergmann et al.
patent: 2005/0239150 (2005-10-01), Bergmann et al.
patent: 2006/0029990 (2006-02-01), Bergmann et al.
patent: 2006/0035221 (2006-02-01), Bergmann et al.
patent: 2006/0234295 (2006-10-01), Bergmann et al.
patent: 0 656 121 (1998-03-01), None
patent: 00/73322 (2000-12-01), None
Yin et al. Participation of different cell types in the restitutive response of the rat liver to periportal injury induced by allyl alcohol Journal of Hepatology 1999; 31: 497-507.
Ozaki et al. Enzyme-Linked Immunosorbent Assay of Carbamoyl phosphate Synthase 1: Plasma Enzyme in Rat Experimental Hepatitis and Clearance. Enzyme protein 1994 95:48:213-221.
Tabuchi et al (Regulation of Genes for inducible Nitric Oxide Synthase and Urea Cycle Enzymes in Rat Liver in Endotoxin Shock Biochemical and biophysical research communications vol. 268, 221-224 (2000).
Cerdan et al. (Role of calcium as an inhibitor of carbamoyl phosphate synthetase I Journal of Biological Chemistry 1984, vol. 259, No. 1, p. 323-331.
Ardawi, M. S. M. “Hepatic Glutamine Metabolism in the Septic Rat,”Clinical Science(London)., 1992, vol. 82, No. 6, pp. 709-716.
Assicot, M. et al. “High Serum Procalcitonin Concentrations in Patients with Sepsis and Infection,”The Lancet., 1993, vol. 341, No. 8844, pp. 515-518.
Beishuizen, A. et al. “Endogenous Mediators in Sepsis and Septic Shock,”Advances in Clinical Chemistry., 1999, vol. 33, pp. 55-131.
Gabay, C. et al. “Acute-Phase Proteins and Other Systemic Responses to Inflammation,”The New England Journal of Medicine., 1999, vol. 340, No. 6, pp. 448-454.
Ghillani, P. et al. “Monoclonal Antipeptide Antibodies as Tools to Dissect Closely Related Gene Products,”Journal of Immunology., 1988, vol. 141, No. 9, pp. 3156-3163.
Ghillani, P. et al. “Identification and Measurement of Calcitonin Precursors in Serum of Patients with Malignant Diseases,”Cancer Research,. 1989, vol. 49, pp. 6845-6851.
Klose, J. “Two-dimensional Electrophoresis of Proteins: An Updated Protocol and Implications for a Functional Analysis of the Genome,”Electrophoresis., 1995, vol. 15, pp. 1034-1059.
Linger et al. “Reverse Transcriptase Motifs in the Catalytic Subunit of Telomerase,”Science., 1997, vol. 276, pp. 561-567.
Mann et al. “Use of Mass Spectrometry-Derived Data to Annotate Nucleotide and Protein Sequence Databases,”Biochemical Sciences., 2001, vol. 26, No. 1, pp. 54-61.
Neubauer et al. “Mass Spectrometry and EST-Database Searching Allows Characterization of the Multi-Protein Spliceosome Complex,”Nature Genetics., 1998, vol. 20, 46-50.
Neuhoff, V. et al. “Improved Staining of Proteins in Polyacrylamide Gels Including Isoelectric Focusing Gels with Clear Background at Nanogram Sensitivity using Coomassie Brilliant Blue G-250 and R-250,”Electrophoresis., 1988, vol. 9, pp. 255-262.
Nielsen, S. et al. “Acute Systemic and Local Inflammation Decreases Hepatic Expressions of Urea Cycle Enzymes,”Journal of Hepatology., 2000, vol. 32 (Suppl. 2), pp. 161.
Otto, A. et al. “Identification of Human Myocardial Proteins Separated by Two-Dimensional Electrophoresis using an Effective Sample Preparation for Mass Spectrometry,”Electrophoresis., 1996, vol. 17, pp. 1643-1650.
Ozaki, M. et al. “Enzyme-Linked Immunosorbent Assay of Carbamoylphosphate Synthetase I: Plasma Enzyme in Rat Experimental Hepatitis and its Clearance,”Enzyme Protein., 1994, vol. 48, No. 4, pp. 213-221.
Redl, H. et al. “Non-Human Primate Models of Sepsis,”Sepsis., 1998, vol. 2, pp. 243-253.
Redl, H. et al. “Procalcitonin Release Patterns in a Baboon Model of Trauma and Sepsis: Relationship to Cytokines and Neopterin,”Crit Care Med., 2000, vol. 28, No. 11, pp. 3659-3663.
Schimke, R. “Adaptive Characteristics of Urea Cycle Enzymes in the Rat,”Journal of Biological Chemistry., 1962, vol. 237, No. 2, pp. 459-468.
Szondy, Z. et al. “Effect of Polyamines on the Carbamoylphosphate Synthetase Activity of Cad Protein,”Database: BioSciences Information Service., 1989, vol. 24, pp. 107-118.
Tabuchi, S. et al. “Regulation of Genes for Inducible Nitric Oxide Synthase and Urea Cycle Enzymes in Rat Liver in Endotoxin Shock,”Ciochemical and Ciophysical Research Communications., 2000, vol. 268, No. 1, pp. 221-224.
Tygstrup, N. et al. “Expression of Liver Functions Following Sub-Lethal and Non-Lethal Doses of Allyl Alcohol and Acetaminophen in the Rat,”Journal of Hepatology., 1997, vol. 27, No. 1, pp. 156-162.
Yin, L. et al. “Participation of Different Cell Types in the Restitutive Response ot the Rat Liver to Periportal Injury Induced by Allyl Alcohol,”Journal of Hepatology., 1999, vol. 31, No. 3, pp. 497-507.
Office Action dated Sep. 24, 2007 in co-pending U.S. Appl. No. 10/496,173.
Office Action dated Sep. 4, 2007 in co-pending U.S. Appl. No. 10/496,096.
Notice of Allowability in co-pending U.S. Appl. No. 10/511,758.
Office Action dated Jun. 27, 2007 in co-pending U.S. Appl. No. 10/496,250.
Office Action dated Jan. 7, 2008 in co-pending U.S. Appl. No. 10/497,679.
Office Action dated Jan. 29, 2008 in co-pending U.S. Appl. No. 10/516,618.
Bergmann Andreas
Struck Joachim
Uhlein Monika
B.R.A.H.M.S. Aktiengesellschaft
Bell Charles E.
Gebreyesus Kagnew
Heslin Rothenberg Farley & & Mesiti P.C.
Mondesi Robert B.
LandOfFree
Uses of carbamoyl phosphate synthetase for the diagnois of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Uses of carbamoyl phosphate synthetase for the diagnois of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Uses of carbamoyl phosphate synthetase for the diagnois of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4010254