Useful mutations of bacterial alkaline protease

Details Useful mutations of bacterial alkaline protease Useful mutations of bacterial alkaline protease

2005-06-21

2005-06-21

Achutamurthy, Ponnathapura (Department: 1652)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S069100, C435S221000, C435S252310, C435S320100

Reexamination Certificate

active

06908991

ABSTRACT:
The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.

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