Use of Zn-protoporphyrin for hepatitis treatment

Details Use of Zn-protoporphyrin for hepatitis treatment Use of Zn-protoporphyrin for hepatitis treatment

1989-10-18

1991-02-26

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514894, 424 9, A61K 4900, A61F 31585

Patent

active

049962000

ABSTRACT:
There is provided an oral antihepatopathic composition comprising protoporphyrin IX-Zn(II) complex. By oral administration, the complex can suppress the elevation of GPT and GOT as well as the increase of liver weight in a living body suffering from hapatic disorder, which contributes to prevention or relief of the disease.

REFERENCES:
Qato et al.-Biochem. J. (1985), 226, 51-57.
Maines et al.-Biochem. J. (1984), 217, 409-417.
Maines-Biochimica Et Biophysica Acta, 673 (1981), 339-350.
"Bilirubin Metabolism and the Hereditary Hyperbilirubinemias", Paul D. Berk, Gastroenterology, vol. 5, 4th Edition, 1985, pp. 2732-2797.

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