Use of β-adrenoceptor antagonists for the manufacture...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S912000

Reexamination Certificate

active

07081482

ABSTRACT:
The invention is directed to the use of β-adrenoceptor antagonists for the manufacture of a medicament for the treatment of disorders of the outer retina.

REFERENCES:
patent: 4252984 (1981-02-01), Manoury et al.
patent: 4311708 (1982-01-01), Manoury et al.
patent: 4443432 (1984-04-01), Garabedian et al.
patent: WO 98/10758 (1998-03-01), None
Osborne, et al., “Topically applied betaxolol attenuates NMDA-induced toxicity to ganglion cells and the effects of ischaemia to the retina,” Exp. Eye Research, vol. 69:331-342, 1999.
Osborne, et al., “Neuroprotection in Relation to Retinal Ischemia and Relevance to Glaucoma,” Survey of Ophthalmology, vol. 43(1):S103-S128, Jun. 1999.
Fabianova, et al., “Centralna serozna chorioretinopatia-liecba betablokatormi,” Ceska A Slovenska Oftamologie, vol. 54(6):401-404, Nov. 1998.
Young, Richard, “Solar radiation and age-related macular degeneration,” Current Research, vol. 32(4);252-269, Jan.-Feb. 1988.
Noell, et al., “Retinal damage by light in rats,” Investigative Ophthalmology, vol. 5(5):450-472, Oct. 1966.
Bressler, et al., “Age-related macular degeneration,” Survey Ophthalmology, vol. 32(6):375-413, May-Jun. 1988.
Curico, et al., “Photoreceptor loss in age-related macular degeneration,” Investigative Ophthalmology & Visual science, vol. 37(7):1236-1249, Jun. 1996.
Ge-Zhi, et al., “Apoptosis in human retinal degenerations,” Transactions of the.American Ophthalmology Society., vol. 94:411-430, 1996.
Abler, et al., “Photic injury triggers apoptosis of photoreceptor cells,” Research Communication in Molecular Pathology and Pharmacology, vol. 92(2):177-189, May 1996.
Taylor, et al., “Long-term effects of visable light on the eye,” Archives of Ophthalmology, vol. 110:99-104, Jan. 1992.
Naash, et al., “Induced acceleration of photoreceptor degeneration transgenic mice expressing mutant rhodopsin,” Investigative Ophthalmology & Visual Science, vol. 37(5): 775-782, Apr. 1996.
LaVail, et al., “Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light,” Proceedings of the National Academy of Science, vol. 89:11249-11253, Dec. 1992.
Faktorovich, et al., “Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor,” Nature, vol. 347:83-86, Sep. 1990.
Organisciak, et al., “The protective effect of ascorbate in retinal light damage of rats,” Investigative Ophthalmology & Visual Science, vol. 26:1580-1588, Nov. 1985.
Organisciak, et al., “Protection by dimethylthiourea against retinal light damage in rats,” Investigative Ophthalmology & Visual Science, vol. 33(5):1599-1609, Apr. 1992.
Lam, et al., “Amekioration of tetinal photic injury in albino rats by dimethylthiourea,” Archives of Ophthalmology, vol. 108:1751-1757, Dec. 1990.
Kozaki, et al., “Light-induced retinal damage in pigmented rabbit—2, Effect of alpha-tocopherol,” Nippon Ganka Gakkai Zasshi, vol. 98:948-954, Oct. 1998.
Rapp, et al., “Evaluation of retinal susceptibility to light damage in pigmented rats supplemented with beta-carotene,” Current Eye Research, vol. 15:219-223; 1995.
Li, et al., “Amelioration of retinal photic injury by a combination of flunarizine and dimethylthiourea,” Experience Eye Research, vol. 56:;71-78, 1993.
Edward, et al., “Amelioration of light-induced retinal degeneration by a calcium overload blocker,” Archives of Ophthalmology, vol. 109:554-562, Apr. 1991.
Lam, et al., “Methylprednisolone therapy in laser injury of the retina,” Graefes Archives of Clinical & Experimental Ophthalmology, vol. 231:729-736, 1993.
Fu, et al., “Dexamethasone ameliorates retinal photic injury in albino rats,” Experimental Eye Research, vol. 54:583-594, 1992.
Collier, et al., “Prevention of photic induced retinal injury by eliprodil,” Investigative Ophthalmology & Visual Science, vol. 40(4):S159, Mar. 1999.
Li, et al., “Desferrioxamine ameliorates retinal photic injury in albino rats,” Current Eye Research, vol. 10(2):133-144, 1991.
Osborne, et al., “In vivo and in vitro experiments show that betaxolol is a retinal neuroprotective agent,” Brain Research, vol. 751:113-123, 1997.
Hester, et al., “The direct vascular relaxing action of betaxolol, carteolol and timolol in porcine long posterior ciliary artery,” Survey of Ophthalmology, vol. 38:S125-S134, May 1994.
Yu, et al., “Effect of beta blockers and CA2+ entry blockers on ocular vessels,” Vascular Risk Factors and Neuroprotection in Glaucoma, (Drance, S. ed.) pp. 123-134, Update, 1996.
Hoste, et al., “The relaxant action of bataxolol on isolated bovine retinal microarteries,” Current Eye Research, vol. 13:483-487, 1994.
Bessho, et al., “Vascular effects of betaxolol, a cardioselective B-adrenoceptor antagonist, in isolated rat arteries,”Japan Journal of Pharmacology, vol. 55:351-358, 1991.
Shahinfar, et al., “A pathologic study of photoreceptor cell death in retinal photic injury,” Current Eye Research, vol. 10(1):47-59, 1991.
Abler, et al., “Photoic injury triggers apoptosis of photoreceptor cells,” Investigative Ophthalmology & Visual Science, vol. 35(4):S1517, Mar. 1994.
Chang, et al., “Apoptotic photoreceptor cell death after traumatic retinal detachment in humans,” Archives of Ophthalmology, vol. 113:880-886, Jul. 1995.
Portera-Cailliau, et al., “Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa,” Proceedings of National Academy of Science (U.S.A.); vol. 91:974-978, Feb. 1994.
Buchi, Ernst R., “Cell death in the rat retina after a pressure-induced ischaemia-reperfusion insult: An electron microscopic study. I. Ganglion cell layer and inner nuclear layer,” Experience Eye Research. vol. 55:605-613. 1992.
Quigley, et al., “Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis,” Investigative Ophthalmology & Visual Science, vol. 36(5):774-786, Apr. 1995.
Zigman, et al., “The response of mouse ocular tissues to continuous near-UV light exposure,” Investigative Ophthalmology & Visual Science, vol. 14(9):710-713, Sep. 1975.
Kuwahara, et al., “Retinal damage by visible light,” Archives of Ophthalmology, vol. 79:69-78, 1968.
LaVail, Matthew M., “Survival of some photoreceptor cells in ablino rats following long-term exposure to continuous light,” Investigative Ophthalmology & Visual Science, vol. 15(1):64-70, Jan. 1976.
Lawwill, Theodore, “Effects of prolonged exposure of rabbit retina to low-intensity light,” Investigative Ophthalmology & Visual Science, vol. 12(1):45-51, Jan. 1973.
Collier, et al., “Comparison of retinal photochemical lesions after exposure to near-uv or short-wavelength visible radiation,” Inherited and Environmentally Induced Retinal Degenerations, Alan R. Liss, Inc., New York, pp. 569-575.
Collier, et al., “Temporal sequence of changes to the gray squirrel retina after near-uv exposure,” Investigative Ophthalmology & Visual Science, vol. 30(4):631-637, Apr. 1989.
Tso, M.O.M., “Photic maculopathy in rhesus monkey,” Investigative Ophthalmology & Visual Science, vol. 12(1):17-34; Jan. 1973.
Ham, et al., “The nature of retinal radiation damage: Dependence on wavelength, power level and exposure time,” Vision Research, vol. 20:1105-1111, 1980.
Sperling, et al., “Differential spectral photic damage to primate cones,” Vision Research, vol. 20:1117-1125; 1980.
Sykes, et al., “Damage to the monkey retina by broad-spectrum fluorescent light,” Investigative Ophthalmology &

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of β-adrenoceptor antagonists for the manufacture... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of β-adrenoceptor antagonists for the manufacture..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of β-adrenoceptor antagonists for the manufacture... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3541729

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.