Use of von willebrand factor and pharmaceutical formulation

Details Use of von willebrand factor and pharmaceutical formulation Use of von willebrand factor and pharmaceutical formulation

1996-11-06

1999-12-21

Sisson, Bradley L.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

514 12, 435 681, A61K 3514

Patent

active

060050772

ABSTRACT:
The invention relates to the use of von Willebrand Factor (vWF) with a prolonged biological half-life for the production of a preparation for stabilization of blood coagulation Factor VIII (FVIII:C) in a mammal. Additionally, a pharmaceutical preparation is provided comprising a biologically active FVIII:C/vWF complex with improved pharmokinetic properties, said complex containing a vWF with a prolonged biological half-life.

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