Use of vinyl alcohol homopolymer and copolymers for tableting ac

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Biocides; animal or insect repellents or attractants

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424409, 424410, 424468, 424469, 424470, A01N 2534

Patent

active

049903357

ABSTRACT:
Method of making tablets for active ingredient delivery by compressing a mixture of active ingredient and granular, high viscosity, fully hydrolyzed polyvinyl alcohol or copolymer of vinyl alcohol with methyl acrylate or methyl methacrylate. By use of a crystalline, heat treated polymer, a tablet providing quick active ingredient release is obtained. By using an amorphous, non-heat treated polymer a tablet providing prolonged active ingredient release is obtained. By using blends of crystalline and amorphous polymers, tablets having a range of active ingredient release characteristics can be obtained. The granular, high viscosity, fully hydrolyzed polymers provide flowability, compressibility and processing versatility advantages over conventional tablet binders.

REFERENCES:
patent: 3108046 (1963-10-01), Harbit
patent: 4415547 (1983-11-01), Yu et al.
patent: 4499066 (1985-02-01), Moro et al.
patent: 4800087 (1989-01-01), Mehta
patent: 4837032 (1989-06-01), Ortega

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