Use of urinastatin-like compounds to prevent premature delivery

Details Use of urinastatin-like compounds to prevent premature delivery Use of urinastatin-like compounds to prevent premature delivery

1993-11-04

1997-07-22

Schneiner, Toni R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514 8, 514 21, 514653, 514 24, 514420, 514 61, 514192, 514195, 514198, 514 29, 514200, 514209, 424682, 424709, 424 944, 435 71, 435 74, 435 79, 435 791, 435 792, 435 793, 435 794, 435 795, A61K 3800, G01N 3353, G01N 33537, G01N 33543

Patent

active

056503946

ABSTRACT:
The present invention provides a method of diagnosing and treating a pregnant female at risk for impending preterm delivery. The method comprises the step of diagnosing imminent preterm delivery by testing with a method that has a sensitivity of at least 80% and a specificity of at least 80%, or by testing for fetal fibronectin in the female's vaginal or cervical secretions. If imminent preterm delivery is indicated by the test, the next step comprises administering to the female a combination of a tocolytic agent, at least one urinastatin-like compound, and at least one antibiotic. Also provided is a pharmaceutical composition of MGMTSRYFYNGTSMA (SEQ ID NO:1), RAFIQLWAFDAVKGK (SEQ ID NO:2) and an antibiotic.

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