Use of unstructured nucleic acids in assaying nucleic acid...

Details Use of unstructured nucleic acids in assaying nucleic acid... Use of unstructured nucleic acids in assaying nucleic acid...

2008-05-13

2008-05-13

Sisson, Bradley L. (Department: 1634)

Chemistry: analytical and immunological testing

Heterocyclic carbon compound

Hetero-o

C435S006120, C435S287200, C536S023100, C536S024300, C436S800000

Reexamination Certificate

active

07371580

ABSTRACT:
The present invention provides a system and methods for assaying nucleic acid molecules with reduced levels of background signal and enhanced specificity and sensitivity. In particular, the present invention provides a system and methods for detecting, sorting, tracking and characterizing nucleic acid molecules using hybridization assays with reduced levels of undesirable cross hybridization and reduced levels of intramolecular secondary structure.

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