Use of Ulinastatin and its pharmaceutical composition for...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S002600, C424S545000

Reexamination Certificate

active

07470666

ABSTRACT:
The present invention relates to use of Ulinastatin and its pharmaceutical composition for treating and/or preventing Severe Acute Respiratory Syndrome (SARS). Ulinastatin is effective for treating and/or preventing SARS, particularly Acute Lung Injury (ALI) or Acute Respiratory Distress Syndrome (ARDS). Ulinastatin is generally used as the pharmaceutical composition, preferably in the form of freeze-dried powder or aqueous solution for injection.

REFERENCES:
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patent: 0327999 (1992-06-01), None
patent: 2000336041 (2000-12-01), None
patent: 20000335041 (2000-12-01), None
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Manamiya et al. Sasshi Journal. Nihon Kyobu Geka Gakkai 41(12): 2364-2371, abstract only cited. (2003).
Cai, Ming et al., “Effects of Free Radical Scavengers, Methylprednisolone, and Ulinastatin on Acute Xanthine and Xanthine Oxidase-Induced Lung Injury in Rats,” Dept. of Anesthesiology, Nippon Med. School, Tokyo, Japan, pp. 71-78, 1994.

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