Use of tumor necrosis factor as a weight regulator

Details Use of tumor necrosis factor as a weight regulator Use of tumor necrosis factor as a weight regulator

1985-11-26

1987-08-04

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 11, 514 13, 514 14, 530387, 424 85, A61K 3702, A61K 3900

Patent

active

046846239

ABSTRACT:
A method for controlling weight by suppressing the normal metabolism of adipose tissue is disclosed. Administration of tumor necrosis factor (TNF) or a pharmaceutical composition containing it results in suppression of anabolism of adipose cells.

REFERENCES:
Torti, F. M. et al., Science, 229: 867-869.
Beutler, B. et al., Science, 229: 869-871.
J. Exp. Med., vol. 154 (1981), 631-639.
Proc. Nat'l. Acad. Sci., 79, 912-916 (1982).

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