Use of trospium chloride and 2-component system for the same

Details Use of trospium chloride and 2-component system for the same Use of trospium chloride and 2-component system for the same

1997-11-17

1999-12-07

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3144

Patent

active

059984309

ABSTRACT:
Compositions of the anticholinergic agent trospium chloride suitable for localized administration are provided, in the form of an aqueous solution having a pH-value of.gtoreq.4.5, that is prepared prior to administration. Methods of using the provided compositions for treating dysfunctions of the bladder and the urinary system are also provided. The treatment methods are characterized by the intravesicular administration of the inventive composition into the bladder of a patient in need thereof

REFERENCES:
"Intravesikale Spasmolytika", Urologe (B) (1994)34:95, Springer Verlag, Jan. 1994.
Ultrasound Studies of the Effect of Trospium Chloride on Gall Bladder Kinetics, Drug Research, 42(II) Nr. 12 (1993).
Nonoperative Management of Urinary Incontinence, Current Opinion in Obstetrics and Gynecology, 1996 8:347-350.

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