Use of treosulfan and derivatives thereof for treating...

Drug – bio-affecting and body treating compositions – Multiple sclerosis

Reexamination Certificate

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C424S703000, C514S708000, C514S709000, C514S711000

Reexamination Certificate

active

10524144

ABSTRACT:
The invention relates to the use of treosulfan and/or derivatives thereof for producing a pharmaceutical composition used in the treatment of multiple sclerosis.

REFERENCES:
patent: 01 32154 (2001-05-01), None
patent: WO 01/32154 (2001-05-01), None
Fridman, Igor Surface area of Human Skin 2001.
H. Openshaw et al., “Peripheral blood stem cell transplantation in multiple sclerosis with busulfan and cyclophosphamide conditioning: Report of toxicity and immunological monitoring”, Biology of Blood and Marrow Transplantation, vol. 6, No. 5a, pp. 563-575, XP002263510.
Rieckmann, Immunmodulatorische Therapie der Multiplen Sklerose, 2002: 109-118.
Goodin et al, Neurology 58, Jan. 2002, pp. 169-178.
Specialist information “Novantron®” (Wyeth Pharma GmbH), Jan. 2002.
Weissert et al, J. Clin. Invest., 1998, 102:1265-1273.
Weissert et al, The Journal of Immunology, 1998, 160:681-690.
Weissert et al, The Journal of Immunology, 2001, 166:7588-7599.
Hauser et al, N. Engl. J. Med., 1983, 308:173-180.
Openshaw et al, Biology of Blood and Marrow Transplantation 2000, 6:563-575.

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