Use of toremifene and its metabolites for the reversal of multid

Details Use of toremifene and its metabolites for the reversal of multid Use of toremifene and its metabolites for the reversal of multid

1989-08-23

1991-02-05

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514646, A61K 31135

Patent

active

049905384

ABSTRACT:
This invention relates to the use of a compound comprising toremifene or its metabolites N-demethyltoremifene or 4-hydroxytoremifene or its non-toxic pharmaceutically acceptable salts for the reversal of multidrug resistance of cancer cells to cytotoxic drugs in the treatment of cancer with such cytotoxic drugs.

REFERENCES:
Chemical Abstracts, vol. 111, p. 20, 1989, 89809b.

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