Use of TNF for the prevention or treatment of radiation damage

Details Use of TNF for the prevention or treatment of radiation damage Use of TNF for the prevention or treatment of radiation damage

1987-04-14

1989-08-29

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Lymphokine

514 2, 514 12, 514 8, A61K 3702

Patent

active

048615870

ABSTRACT:
The use of TNF for the prophylaxis and therapy of radiaton damage is described.

REFERENCES:
patent: 4275056 (1981-06-01), Takaku et al.
Muir's Textbook of Pathology, 10th Ed. (1976) pp. 23-29, "Cell Damage Due to Ionising Radiation" and p. 259.
Broudy et al., cited in Chem. Abstracts, vol. 105:189177p (1986).
Carswell et al., PNAS U.S.A., vol. 72, No. 9, pp. 3666-3670, Sep. 1975.
Stankovic, cited in Chem. Abstracts, vol. 74:38912q (1971).
Nature, vol. 312, (1984), pp. 724-729.
Broudy et al. (1986), Proc. Natl. Acad. Aci. USA, 83:7467-7471.
Activation of Human Polymorphonuclear Neutrophil Functions by Interferon-.gamma. and Tumor Necrosis Factors, J. of Immuno. (1985)135, No. 3:2069-2073-Shalaby et al.

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