Use of timosaponin Bll in the preparation of a medicament or...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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Reexamination Certificate

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07998936

ABSTRACT:
The invention disclosed the use of timosaponin BII in the preparation of a medicament or product for the prevention and treatment of stroke. The experiments prove that timosaponin BII can improve the neurological symptoms of cerebral ischemic rat, reduce infarct size, relieve brain water edema, improve hemorheology, reduce inflammatory injury of cerebral ischemia.

REFERENCES:
patent: 1212966 (1999-04-01), None
patent: 1451384 (2003-11-01), None
patent: 1451384 (2003-11-01), None
Yang, L.R., “Study on Chemical Component and Pharmacological Action of Anemarrhena Asphodeloides,” (2002), pp. 207-210, vol. 24(4),foreign medical science section of traditional Chinese medicine and Chinese material medicia.
International Search Report for PCT/CN2005/000553 completed on Jun. 23, 2005.
Fu, Y., et al., “Pennogenin glycosides with a spirostanol structure are strong platelet agonists: structural requirement for activity and mode of platelet agonist synergism,”Journal of Thrombosis and Haemostasis, 2007, vol. 6, pp. 524-533.
Guo, L., et al., “Active pharmaceutical ingredients and mechanisms underlying phasic myometrial contractions stimulated with the saponin extract fromParis polyphyllaSm. var.yunnanensisuse for abnormal uterine bleeding,”Human Reproduction, 2008, vol. 23(4), pp. 964-971.
Ma, B., et al., “New Spirostanol Glycosides fromAnemarrhena aspholdeloides,”Planta Med., 1997, vol. 63, pp. 376-379.
Ma, et al., “Studies on the Furostanol Saponins FromAnemarrhena AsphodeloidesBunge ,”Acta Pharmaceutica Sinica, 1996, vol. 31(4), pp. 271-277. Abstract Only.
Saito, S., et al., New Steroidal Saponins from the Rhizomes ofAnemarrhena asphodeloidesBunge (Liliaceae),Chem. Pharm. Bull., 1994, vol. 42(11), pp. 2342-2345.
Wang, et al., G., “Effect of timosaponin A-III fromAnemarrhenae asphodeloidesBunge (Liliaceae), on calcium mobilization in vascular endothelial and smooth muscle cells on vascular tension,”Life Sciences, 2002, vol. 71, pp. 1081-1090.
Zhang, J., et al., “Effect of Steroidal Saponins ofAnemarrhenaeRhizoma on Superoxide Generation in Human Neutrophils,”Biochemical and Biophysical Research Communications, 1999, vol. 259, pp. 636-639.
Zhang, J., et al., “Effect of six steroidal saponins isolated from anemarrhenae rhizome on platelet aggregation and hemolysis in human blood,”Clinica Chimica Acta, 1999, vol. 289, pp. 79-88.
Zhiyun, M., et al., “Timosaponins E1 and E2,”Acta Pharmaceutica Sinica, 1998, vol. 33(9), pp. 693-696. Abstract Only.
Zhiyun, M., et al., “A New Steroidal Saponin from Anemarrhena asphodeloides Bge,”Journal of Shenyang Pharmaceutical University, 1998, vol. 15(4), pp. 254-255. Abstract Only.

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