Use of thiazolidinedione derivatives in the treatment of polycys

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514342, A61R 31425

Patent

active

058744541

ABSTRACT:
Novel methods of using thiazolidinone derivatives and related antihyperglycemic agents to treat populations at risk for developing noninsulin-dependent diabetes mellitus (NIDDM) and complications arising therefrom are disclosed In one embodiment, the compounds of the invention are used to treat polycystic ovary syndrome in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus. In another embodiment, the compounds of the invention are used to treat gestational diabetes in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus.

REFERENCES:
patent: 4287200 (1981-09-01), Kawamatsu et al.
patent: 4572912 (1986-02-01), Yoshioka et al.
patent: 4687777 (1987-08-01), Meguro et al.
patent: 4873255 (1989-10-01), Yoshioka et al.
patent: 4897405 (1990-01-01), Alessi et al.
patent: 5061717 (1991-10-01), Clark et al.
patent: 5120754 (1992-06-01), Clark et al.
patent: 5132317 (1992-07-01), Cantello et al.
patent: 5223522 (1993-06-01), Clark et al.
The New England Journal of Medicine, vol. 319, No. 23, 1988, pp 1500-1506, Saad et al.
Diabetes Care, vol. 15, No. 8, 1992, pp 1075-1078, Hofmann et al.
J. Med. Chem., vol. 35, No. 14, 1992, pp 2617-2626, Sohda et al.
Chemical Abstracts, vol. 119, No. 1, 1993, abstract No. 97.
Annals of the New York Academy of Sciences, vol. 687, 1993, pp 60-64, Dunaif.
Annales D'Endocrinologie (Paris), vol. 53, No. 1, 1992, pp 1-7, Dewailly et al.
Diabetologia, vol. 34, 1991, p. A198, Robinson et al.
PCT International Search Report, PCT/US 94/10187 (1994).
Drugs, 44 (Suppl. 3):29-38, 1992, Lefebvre et al.
The Lancet, 1:870-872, 1988, Polson et al.
Obstetrics & Gynecology, 66:545-552, 1985, Dunaif et al.
Metabolism, 38:1089-1093, 1989, Kraegen et al.
Diabetes, 37:1549-1558, 1988, Fujiwara et al.
Diabetes Res. and Clin. Practice, 11:147-153, 1991, Kuzaza et al.
Diabetes Care, 15:193-203, 1992, Suter et al.
Diabetes Care, 14:1083-1086, 1991, Iwamoto et al.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of thiazolidinedione derivatives in the treatment of polycys does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of thiazolidinedione derivatives in the treatment of polycys, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of thiazolidinedione derivatives in the treatment of polycys will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-307438

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.