Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1989-06-12
1993-03-02
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
43525235, 4353201, C12N 1574, C12N 121, C12N 1509, C12N 1563
Patent
active
051908719
ABSTRACT:
The present invention provides a method for transforming an actinomycete with an integrating vector which has the advantages of high transformation rates into a broad host range, site-specific integration, and stable maintenance without antibiotic selection. Also provided are methods for the increased production of antibiotics and for the production of hybrid antibiotics.
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Cox Karen L.
Kuhstoss Stuart A.
Rao R. Nagaraja
Richardson Mark A.
Schoner Brigitte E.
Eli Lilly and Company
Hamilton Amy E.
LeGuyader John
Schwartz Richard A.
Whitaker Leroy
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