Use of taurocholic acid and its salts as enhancers for calcitoni

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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514966, 514808, 514 21, 514 2, 424433, A61K 3700, A61K 3724

Patent

active

051495376

ABSTRACT:
Suppositories comprising a suppository base, a calcitonin and taurocholic acid or a pharmaceutically acceptable salt thereof exhibit improved bioavailability and are well tolerated.

REFERENCES:
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patent: 4434159 (1984-02-01), Sekine et al.
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patent: 4731210 (1988-03-01), Weder
patent: 4801577 (1989-01-01), Nestor, Jr.
D. Thiebaud, et al., Amer. J. Med. 82, 745-750 (1987).
E. Ziv, et al., Life Sciences, vol. 29, pp. 803-809 (1981).

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