Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-05-10
1994-07-19
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435189, 435 792, 435 794, 435 795, C12Q 126, C12N 902
Patent
active
053308930
ABSTRACT:
An improved method for detecting antibodies is disclosed. The method involves the steps of a) mixing the specimen with a diluent comprising superoxide dismutase, and b) contacting the diluted specimen with at least one recombinant antigen expressed as a fusion protein with superoxide dismutase.
REFERENCES:
Y. Ikeda, et al., "Antibody to Superoxide Dismutase, Autoimmune Hepatitis, and Antibody Tests for Hepatitis C Virus", Lancet 335:1345-1346 (Jun., 1990).
I. G. McFarlane, et al., "Hepatitis C Virus Antibodies in Chronic Active Hepatitis: Pathogenic Factor or False-Positive Result?", Lancet 335:754-57 (Mar., 1990).
Young et al. (1983), Science 222: 778-782.
Hallewell et al. (1985), Nucl. Acids Res. 13(6): 2017-2034.
Dawson George J.
Gilbert Adrienne L.
Kidd Sarah L.
Stewart James L.
Abbott Laboratories
Carter Philip W.
Eggert Joan
Porembski Priscilla E.
Schwartz Richard A.
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