Use of sulfonic derivatives of acylated polyethyleneimine bonded

Details Use of sulfonic derivatives of acylated polyethyleneimine bonded Use of sulfonic derivatives of acylated polyethyleneimine bonded

1986-12-22

1988-01-26

Therkorn, Ernest G.

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

210656, 530368, 530413, 530417, B01D 1508

Patent

active

047215739

ABSTRACT:
Sulfonic derivatives of N-acylated covalently bound, non-crosslinked polyethyleneimine bonded phase silicas of the formula: ##STR1## wherein
is the backbone of a silica gel or glass, n is an integer such that the polyethyleneiminopropyl silane group has an average molecular weight of from about 400 to about 1800; q is an integer of zero or one; R is selected from the group consisting of hydrogen, --CH.sub.2).sub.x H or --CH.sub.2).sub.m COOH where x is an integer of 1 or 2 and m is an integer of zero or 1; when R is hydrogen or --CH.sub.2).sub.x H then R.sup.1 is --CH.sub.2).sub.p COOH where p is an integer of zero or 1, and when R is --CH.sub.2).sub.m COOH then R.sup.1 is selected from the group consisting of hydrogen or --CH.sub.2).sub.y H where y is a integer of zero or 1, are especially useful as solid phases for the purification and separation of proteins having isoelectric points of below about 5.

REFERENCES:
patent: 3987058 (1976-10-01), Saunders
patent: 4505818 (1985-03-01), Mukoyama
patent: 4523997 (1985-06-01), Crane
patent: 4540486 (1985-09-01), Ramsden
patent: 4551245 (1985-11-01), Ramsden
patent: 4606825 (1986-08-01), Crane

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