Use of sulfated saccharides to treat baldness

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 23, 514 25, 514 54, A61K 3170

Patent

active

057671044

ABSTRACT:
A method of treating and/or preventing alopecia (baldness, deficient hair growth) comprises administering to a patient in need thereof a therapeutically or prophylactically effective amount of a sulfated mono-, di- or oligosaccharide or a derivative, salt or complex thereof. The saccharide is preferably polysulfated, such as a polysulfated disaccharide, in particular sucrose, or a derivative, complex or salt thereof. Especially interesting polusulfated disaccharides are sucrose pentasulfate, sucrose hexasulfate, sucrose heptasulfate and sucrose octasulfate, e.g. in the form of a potassium or sodium salt, or in the form of sucralfate.

REFERENCES:
patent: 4912093 (1990-03-01), Michaeli
Caseso et al, Chemical Abstracts, vol. 105 (1986) No. 66249f.
Couclman et al, Chemical Abstracts vol. 108 (1988) No. 56539Y.
The Merk Manual of Diognosis and Therapy 5th. ed. (1987) pp. 2281-2282.

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