Use of sucralfate to treat baldness

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 25, 514 54, A61K 3170

Patent

active

056187980

ABSTRACT:
A method of treating and/or preventing alopecia (baldness, deficient hair growth) comprises administering to a patient in need thereof a therapeutically or prophylactically effective amount of a sulfated mono-, di- or oligosaccharide or a derivative, salt or complex thereof. The saccharide is preferably polysulfated, such as a polysulfated disaccharide, in particular sucrose, or a derivative, complex or salt thereof. Especially interesting polysulfated disaccharides are sucrose pentasulfate, sucrose hexasulfate, sucrose heptasulfate and sucrose octasulfate, e.g. in the form of a potassium or sodium salt, or in the form of sucralfate.

REFERENCES:
patent: 4912093 (1990-03-01), Michaeli
Cassero, Chemical Abstracts, vol. 105 (8) (1986) No. 66249f.
The Merck Manual, 15th ed (1987) pp. 2281-2282.
Couchman et al, Chemical Abstracts, vol. 108 (7), No. 565394.
Gonzalez, et al., Conn's Current Therapy, 599-603 (1984); Latest Approved Method of Treatment for the Practicing Physician.
W. Scott Brooks, Jr., American Journal of Gastroenterology 80:206-209 (1985); Sucralfate: Nonulcer Uses.

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