Use of substituted quinone electron transfer agents in analytica

Details Use of substituted quinone electron transfer agents in analytica Use of substituted quinone electron transfer agents in analytica

1985-02-07

1988-05-24

Marantz, Sidney

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving oxidoreductase

422 56, 435 29, 435 34, 435805, 436 93, 436169, 436904, C12Q 102, C12Q 126, G01N 3300, G01N 3350

Patent

active

047466073

ABSTRACT:
Certain substituted benzo- and naphthoquinone electron transfer agents are useful in analytical compositions, elements and methods, e.g. for determinations of living cells. These electron transfer agents are capable of being reduced by an analyte, and the reduced electron transfer agent, in turn, reduces another compound providing a detectable species (e.g. a dye). The reduction potential (E.sub.1/2) of the electron transfer agents useful inthis invention is in the range of from about -320 to about +400 mV as measured in an aqueous buffer solution at pH 7.

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Lin et al, J. Med. Chem., 17(5), pp. 558-561 (1974).
Lin et al, J. Med. Chem., 17(7), pp. 668-672 (1974).

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