Use of substituted isopropylaminopropanols for inducing inotropi

Details Use of substituted isopropylaminopropanols for inducing inotropi Use of substituted isopropylaminopropanols for inducing inotropi

1976-06-25

1978-03-21

Meyers, Albert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424311, 424330, A61K 31235, A61K 3122, A61K 31135

Patent

active

040804712

ABSTRACT:
A method for inducing increased inotropic effects of the human heart without inducing arrhythmogenic effects, but providing an antiarrhythmogenic effect therein. The method is effected by administering to mammals, including man, a compound of the formula ##STR1## wherein R is selected from the group consisting of hydrogen or ##STR2## wherein R' is selected from the group consisting of straight or branched aliphatic alkyl having 1 to 7 carbon atoms, phenyl, benzyl, and phenylethyl, wherein the phenyl nucleus may be further substituted with alkyl having 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms, alkoxyalkyl having 2 to 8 carbon atoms or halogen, in any position.

REFERENCES:
patent: 3501769 (1970-03-01), Crowther et al.
patent: 3740443 (1973-06-01), Koppe et al.
patent: 3857891 (1974-12-01), Holmes et al.
Chemical Abstracts, vol. 72, 1970, pp. 355-356, (111007).

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