Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-10-17
1992-02-25
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31415
Patent
active
050914022
ABSTRACT:
This invention relates to local epidural or intraspinal use of compounds of the formula: ##STR1## where X is H or CH.sub.3 and R.sub.1 and R.sub.2, which can be the same or different, are each H or CH.sub.3 and their stereoisomers and their non-toxic, pharmaceutically acceptable salts. Especially useful are the compounds known under the generic names medetomidine ((.+-.)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole), dexmedetomidine (+)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole and detomidine 4-(2,3-dimethylbenzyl)-1H-imidazole.
Kalso Eija
Lammintausta Risto
Friedman Stanley J.
Orion-yhtyma Oy
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