Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-04-19
1996-08-20
Henley, III, Raymond
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514245, 514318, 514341, 514357, 514400, A61K 3144, A61K 3153, A61K 31445, A61K 31415
Patent
active
055479650
ABSTRACT:
The invention relates to the use of substituted amines for the treatment and prevention of brain function disorders. The substituted amines are suitable on the basis of their properties as agonistic or antagonistic ligands for nicotinergic receptors, in particular for the treatment and prevention of senile and presenile dementia and dementia of the Alzheimer type, and of depressions.
REFERENCES:
patent: 4531002 (1985-07-01), Harris
patent: 4590272 (1986-05-01), Shiokawa et al.
patent: 4647570 (1987-03-01), Shiokawa et al.
patent: 4687845 (1987-08-01), Hollowood et al.
patent: 4806553 (1989-02-01), Shiokawa et al.
patent: 4812454 (1989-03-01), Shiokawa et al.
patent: 4812571 (1989-03-01), Shiokawa et al.
patent: 4849432 (1989-07-01), Shiokawa et al.
patent: 4914113 (1990-04-01), Shiokawa et al.
patent: 4918086 (1990-04-01), Gsell
patent: 4918088 (1990-04-01), Gsell
patent: 4948798 (1990-08-01), Gsell
patent: 4963572 (1990-10-01), Gsell
patent: 4963574 (1990-10-01), Bachmann et al.
patent: 4988712 (1991-01-01), Shiokawa et al.
patent: 5034404 (1991-07-01), Uneme et al.
patent: 5034524 (1991-07-01), Shiokawa et al.
patent: 5039686 (1991-08-01), Davies et al.
patent: 5049571 (1991-09-01), Gsell
patent: 5166164 (1992-11-01), Nanjo et al.
patent: 5175301 (1992-12-01), Minamida et al.
patent: 5192778 (1993-03-01), Kodaka et al.
patent: 5204359 (1993-04-01), Shiokawa et al.
patent: 5204360 (1993-04-01), Shiokawa et al.
patent: 5238949 (1993-08-01), Shiokawa et al.
patent: 5256679 (1993-10-01), Minamida et al.
patent: 5280123 (1994-01-01), Nanjo et al.
patent: 5304566 (1994-04-01), Ishimitsu et al.
patent: 5384324 (1995-01-01), Shiokawa et al.
D. Collerton, Neurosscience, vol. 19, pp. 1-28, 1986.
R. T. Bartus, et al., Science, vol. 217, pp. 408-417, 1982.
P. T. Francis, et al., New England J. Med., vol. 313, pp. 7-11, 1985.
K. J. Kellar, et al., Brain Res., vol. 436, pp. 62-68, 1987.
A. Nordberg, et al., Neurosci. Letters, vol. 86, pp. 317-321, 1988.
E. Giacobini, J. Neurosci. Res., vol. 27, pp. 548-560, 1990.
A. Nordberg, et al., Neurosci. Letters, vol. 86, pp. 747-758, 1992.
D. D. Flynn, et al., J. Neurochemistry, vol. 47, pp. 1948-1954, 1986.
M. W. Decker, et al., Brain Res., vol. 572, pp. 281-285, 1992.
S. Poincheval-Fuhrman, et al., Pharmacology, vol. 4, pp. 535-539 (1993).
E. D. Levin, et al., Cognitive Brain Res., vol. 1, pp. 137-143, 1993.
M. W. Decker, et al., Pharmacol. Biochem. Behav., vol. 45, pp. 571-576, 1993.
A. V. Terry, et al., Pharmacol. Biochem. Behav., vol. 45, pp. 925-929, 1993.
D. G. Linville, et al., J. Pharmacol. Exp. Ther., vol. 267, pp. 440-448, 1993.
P. A. Newhouse, et al., Psychopharmacology, vol. 95, pp. 171-175, 1988.
B. Sahakian, Br. J. Psychiatry, vol. 154, pp. 797-800, 1989.
DSM III-R, American Psychiatric Association, APA Press, Washington, D.C., 1987.
J. D. Brioni, et al., Eur. J. Pharmacol., vol. 238, pp. 1-8, 1993.
E. C. Hulme, Editor, Receptor-Ligand Interactions, Oxford University Press, pp. 1-458, 1992.
T. Chard, An Introduction to Radioimmunoassay and Related Techniques; Elsevier, Amsterdam, statistische Auswertung per Computer, pp. 163-171, 1990.
Derwent Abstract of JP 03-220,176, (Sep. 27, 1991).
Derwent Abstract of JP 03-255,072, (Nov. 13, 1991).
Derwent Abstract of JP 03-279,359, (Dec. 10, 1991).
Derwent Abstract of JP 03-246,283, (Nov. 1, 1991).
Derwent Abstract of JP 63-287,764, (Nov. 24, 1988).
Derwent Abstract of JP 63-07,857, (Dec. 15, 1988).
Derwent Abstract of JP 02-207,083 (Aug. 16, 1990).
Kr uger Bernd-Wieland
Maelicke Alfred
Maurer Fritz
Methfessel Christoph
Schmidt Bernard
Bayer Aktiengesellschaft
Henley III Raymond
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