Use of substituted 3,4-dihydro-2H-benzopyrans as remedies for ob

Details Use of substituted 3,4-dihydro-2H-benzopyrans as remedies for ob Use of substituted 3,4-dihydro-2H-benzopyrans as remedies for ob

1993-01-14

1994-11-15

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514212, 514337, 514826, A61K 3155, A61K 3144, A61K 3140

Patent

active

053648781

ABSTRACT:
The use of substituted 3,4-dihydro-2H-benzopyrans as remedies for obstructive functional disorders of the lungs and/or disorders of the efferent urinary passages
The use of 3,4-dihydro-2H-benzo[b]pyrans of the formula I ##STR1## in which R.sup.1 represents H, OH, (C.sub.1 -C.sub.2)-alkoxy, (C.sub.1 -C.sub.2)-alkyl or NR.sup.4 R.sup.5, where R.sup.4 and R.sup.5 are identical or different and represent H, (C.sub.1 -C.sub.2)-alkyl or (C.sub.1 -C.sub.3)-alkyl-carbonyl,

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Ashwood et al., 1986, Synthesis & Antihypertensive Activity of 4-(Cyclic amido)-2H-1-benzopyrans, J. Med. Chem. 29:2194-2201.
Englert, et al., "Airway Pharmacology of the Potassium Channel Opener, HOE 234, in Guinea Pigs: in Vitro and in Vivo Studies," European Journal of Pharmacology, vol. 210, pp. 69-75 (1992).

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