Use of sterically stabilized cationic liposomes to...

Details Use of sterically stabilized cationic liposomes to... Use of sterically stabilized cationic liposomes to...

2002-07-29

2010-02-23

Epps-Smith, Janet L. (Department: 1633)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

C424S450000, C435S325000, C514S04400A

Reexamination Certificate

active

07666674

ABSTRACT:
Sterically stabilized cationic liposomes (SSCL) encapsulating a K type oligodeoxynucleotide (ODN) including a CpG motif are disclosed. These SSCL encapuslating a K type ODN can be used to effectively deliver the ODN to a cell. A novel method is also disclosed for producing the SSCL encapsulating the K type ODN. Administration of the SSCL encapsulating a K type ODN and a chemotherapeutic agent, such as a chimeric molecule comprising a targeting molecule selected from the group consisting of an IL-13, and an anti-IL-13 receptor antibody; and an effector molecule selected from the group consisting of aPseudomonasexotoxin, a Diphtheria toxin, and a radionuclide, can be used to dramatically reduce the growth of solid tumors.

REFERENCES:
patent: 2215233 (1940-09-01), Ruskin
patent: 3906092 (1975-09-01), Hilleman et al.
patent: 3911117 (1975-10-01), Ender
patent: 3914450 (1975-10-01), Robbins et al.
patent: 4469863 (1984-09-01), Ts'o et al.
patent: 4544559 (1985-10-01), Gil et al.
patent: 4741914 (1988-05-01), Kimizuka et al.
patent: 4758553 (1988-07-01), Ogoshi
patent: 4806376 (1989-02-01), Saeki et al.
patent: 4956296 (1990-09-01), Fahnestock
patent: 4963387 (1990-10-01), Nakagawa et al.
patent: 4994442 (1991-02-01), Gil et al.
patent: 5023243 (1991-06-01), Tullis
patent: 5066500 (1991-11-01), Gil et al.
patent: 5231085 (1993-07-01), Alexander et al.
patent: 5234811 (1993-08-01), Beutler et al.
patent: 5248670 (1993-09-01), Draper et al.
patent: 5268365 (1993-12-01), Rudolph et al.
patent: 5288509 (1994-02-01), Potman et al.
patent: 5488039 (1996-01-01), Masor et al.
patent: 5492899 (1996-02-01), Masor et al.
patent: 5585479 (1996-12-01), Hoke et al.
patent: 5591721 (1997-01-01), Agrawal et al.
patent: 5602109 (1997-02-01), Masor et al.
patent: 5612060 (1997-03-01), Alexander
patent: 5614191 (1997-03-01), Puri et al.
patent: 5650156 (1997-07-01), Grinstaff et al.
patent: 5663153 (1997-09-01), Hutcerson et al.
patent: 5679397 (1997-10-01), Kuroda et al.
patent: 5684147 (1997-11-01), Agrawal et al.
patent: 5700590 (1997-12-01), Masor et al.
patent: 5712256 (1998-01-01), Kulkarni et al.
patent: 5723335 (1998-03-01), Hutcerson et al.
patent: 5786189 (1998-07-01), Loct et al.
patent: 5804566 (1998-09-01), Carson et al.
patent: 5840705 (1998-11-01), Tsukuda
patent: 5849719 (1998-12-01), Carson et al.
patent: 5895652 (1999-04-01), Giampapa
patent: 5919456 (1999-07-01), Puri et al.
patent: 5922766 (1999-07-01), Acosta et al.
patent: 5976580 (1999-11-01), Ivey et al.
patent: 5980958 (1999-11-01), Naylor et al.
patent: 5994126 (1999-11-01), Stienman et al.
patent: 6008202 (1999-12-01), Huang et al.
patent: 6022853 (2000-02-01), Kuberasampath et al.
patent: 6194388 (2001-02-01), Krieg et al.
patent: 6207646 (2001-03-01), Krieg et al.
patent: 6214806 (2001-04-01), Krieg et al.
patent: 6218371 (2001-04-01), Krieg et al.
patent: 6239116 (2001-05-01), Krieg et al.
patent: 6339068 (2002-01-01), Krieg et al.
patent: 6406705 (2002-06-01), Davis et al.
patent: 6423539 (2002-07-01), Fong et al.
patent: 6428788 (2002-08-01), Debinski et al.
patent: 6429199 (2002-08-01), Krieg et al.
patent: 6498148 (2002-12-01), Raz
patent: 6514948 (2003-02-01), Raz et al.
patent: 6534062 (2003-03-01), Krieg et al.
patent: 6552006 (2003-04-01), Raz et al.
patent: 6562798 (2003-05-01), Schwartz
patent: 6589940 (2003-07-01), Raz et al.
patent: 6610661 (2003-08-01), Carson et al.
patent: 6613751 (2003-09-01), Raz et al.
patent: 6653292 (2003-11-01), Krieg et al.
patent: 2001/0034330 (2001-10-01), Kensil
patent: 2001/0036462 (2001-11-01), Fong et al.
patent: 2001/0044416 (2001-11-01), McCluskie et al.
patent: 2001/0046967 (2001-11-01), Van Nest
patent: 2002/0006403 (2002-01-01), Yu et al.
patent: 2002/0028784 (2002-03-01), Van Nest
patent: 2002/0042383 (2002-04-01), Yew et al.
patent: 2002/0042387 (2002-04-01), Raz et al.
patent: 2002/0055477 (2002-05-01), Van Nest et al.
patent: 2002/0064515 (2002-05-01), Krieg et al.
patent: 2002/0065236 (2002-05-01), Yew et al.
patent: 2002/0086295 (2002-07-01), Raz et al.
patent: 2002/0086839 (2002-07-01), Raz et al.
patent: 2002/0090724 (2002-07-01), Taylor et al.
patent: 2002/0091095 (2002-07-01), Phillips et al.
patent: 2002/0091097 (2002-07-01), Bratzler et al.
patent: 2002/0098199 (2002-07-01), Van Nest et al.
patent: 2002/0098205 (2002-07-01), Choi et al.
patent: 2002/0098980 (2002-07-01), Choi et al.
patent: 2002/0107212 (2002-08-01), Van Nest et al.
patent: 2002/0110569 (2002-08-01), Granoff et al.
patent: 2002/0111323 (2002-08-01), Martin et al.
patent: 2002/0136776 (2002-09-01), Fang et al.
patent: 2002/0137714 (2002-09-01), Kandimalla et al.
patent: 2002/0142974 (2002-10-01), Kohn et al.
patent: 2002/0142977 (2002-10-01), Raz et al.
patent: 2002/0142978 (2002-10-01), Raz et al.
patent: 2002/0156033 (2002-10-01), Bratzler et al.
patent: 2002/0164341 (2002-11-01), Davis et al.
patent: 2002/0165178 (2002-11-01), Schetter et al.
patent: 2002/0183272 (2002-12-01), Johnston et al.
patent: 2002/0197269 (2002-12-01), Lingnau et al.
patent: 2002/0198165 (2002-12-01), Bratzler et al.
patent: 2003/0003579 (2003-01-01), Kadowaki et al.
patent: 2003/0022849 (2003-01-01), Chang
patent: 2003/0022852 (2003-01-01), Van Nest et al.
patent: 2003/0026782 (2003-02-01), Krieg
patent: 2003/0026801 (2003-02-01), Weiner et al.
patent: 2003/0049266 (2003-03-01), Fearon et al.
patent: 2003/0050261 (2003-03-01), Krieg et al.
patent: 2003/0050263 (2003-03-01), Krieg et al.
patent: 2003/0050268 (2003-03-01), Krieg et al.
patent: 2003/0052839 (2003-03-01), Binley et al.
patent: 2003/0055014 (2003-03-01), Bratzler
patent: 2003/0059773 (2003-03-01), Van Nest et al.
patent: 2003/0060440 (2003-03-01), Klinman et al.
patent: 2003/0064064 (2003-04-01), Dina
patent: 2003/0072762 (2003-04-01), Van de Winkel et al.
patent: 2003/0073142 (2003-04-01), Chen et al.
patent: 2003/0078223 (2003-04-01), Raz et al.
patent: 2003/0091599 (2003-05-01), Davis et al.
patent: 2003/0092663 (2003-05-01), Raz
patent: 2003/0096417 (2003-05-01), Fischer
patent: 2003/0100527 (2003-05-01), Krieg et al.
patent: 2003/0104044 (2003-06-01), Semple et al.
patent: 2003/0104523 (2003-06-01), Lipford et al.
patent: 2003/0109469 (2003-06-01), Carson et al.
patent: 2003/0119773 (2003-06-01), Raz et al.
patent: 2003/0119774 (2003-06-01), Foldvari et al.
patent: 2003/0119776 (2003-06-01), Phillips et al.
patent: 2003/0125284 (2003-07-01), Raz et al.
patent: 2003/0129251 (2003-07-01), Van Nest et al.
patent: 2003/0130217 (2003-07-01), Raz et al.
patent: 2003/0133988 (2003-07-01), Fearon et al.
patent: 2003/0135875 (2003-07-01), Ehrhardt et al.
patent: 2003/0138413 (2003-07-01), Vicari et al.
patent: 2003/0138453 (2003-07-01), O'Hagan et al.
patent: 2003/0139364 (2003-07-01), Krieg et al.
patent: 2003/0143213 (2003-07-01), Raz et al.
patent: 2003/0143743 (2003-07-01), Schuler et al.
patent: 2003/0144229 (2003-07-01), Klinman et al.
patent: 2003/0147870 (2003-08-01), Raz et al.
patent: 2003/0148316 (2003-08-01), Lipford et al.
patent: 2003/0148976 (2003-08-01), Krieg et al.
patent: 2003/0148983 (2003-08-01), Fontoura et al.
patent: 2003/0157717 (2003-08-01), Draghia-Akli
patent: 2003/0158136 (2003-08-01), Rice et al.
patent: 2003/0165478 (2003-09-01), Sokoll
patent: 2003/0166001 (2003-09-01), Lipford
patent: 2003/0170273 (2003-09-01), O'Hagan et al.
patent: 2003/0171321 (2003-09-01), Schmidt et al.
patent: 2003/0175731 (2003-09-01), Fearon et al.
patent: 2003/0176373 (2003-09-01), Raz et al.
patent: 2003/0176389 (2003-09-01), Raz et al.
patent: 2003/0180320 (2003-09-01), Darju et al.
patent: 2003/0181406 (2003-09-01), Schetter et al.
patent: 2003/0185848 (2003-10-01), Johnston et al.
patent: 2003/0185900 (2003-10-01), Choi et al.
patent: 2003/0186921 (2003-10-01), Carson et al.
patent: 2003/0191079 (2003-10-01), Krieg et al.
patent: 2003/0199466 (2003-10-01), Fearon et al.
patent: 2003/0203861 (2003-10-01), Carson et al.
patent: 2003/0206967 (2003-11-01), Choi et al.
patent: 2003/0207287 (2003-11-01), Short
patent: 2003/0212026 (2003-11-01), Krieg et al.
patent: 2003/0212028 (2003-11-01), Raz et al.
patent: 2003/0216340 (2003-11-01), Van Nest et al.

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