Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-06-04
1996-11-12
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514885, A61K 31445, A61K 31415
Patent
active
055740413
ABSTRACT:
A method for suppressing an immune response in a mammal by treating the mammal with an effective amount of spiperone derivative that is without significant neuroleptic effect due to decreased binding to serotonin and/or dopamine receptors as compared with unmodified or uncomplexed spiperone, or due to topical application which maximizes local immunosuppression while limiting systemic absorption and neuroleptic effects. The spiperone derivatives are capable of inhibiting classic contact hypersensitivity reactions.
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Arndt Kenneth A.
Galli Stephen J.
Meltzer Peter C.
Razdan Raj K.
Sard Howard P.
Beth Israel Hospital Association
Cebulak Mary C.
Robinson Allen J.
Zalesky Cheryl K.
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