Use of snake venoms for treatment of neurological and related di

Details Use of snake venoms for treatment of neurological and related di Use of snake venoms for treatment of neurological and related di

1981-04-07

1982-07-27

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

424 98, A61K 3900, A61K 3558

Patent

active

043417620

ABSTRACT:
The present invention provides stable compositions of matter including venoms and/or venom fractions extracted from various elapid and viperid snakes, the present compositions of matter having pharmacological activity and being further useful in treating the symptoms of neurological and other disorders, particularly disorders which are caused by malfunction of the immune mechanisms. The present compositions of matter generally include a post-synaptic component capable of binding to nicotinic acetylcholine receptors of cells, a pre-synaptic component capable of inhibition of acetylcholine release, and a viperid component considered to be stimulative of the immune system. Methods of preparation and use of the present compositions of matter are also disclosed.

REFERENCES:
patent: 4012502 (1977-03-01), Philpot
patent: 4126676 (1978-11-01), Sanders
Okonogi et al.-Chem. Abst. vol. 92 (1980) p. 135, 396d.

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