Use of simple amino acids to form porous particles

Details Use of simple amino acids to form porous particles Use of simple amino acids to form porous particles

2007-08-07

2007-08-07

Kishore, Gollamudi S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S046000, C424S498000, C424S502000, C424S001290, C424S009100

Reexamination Certificate

active

09644320

ABSTRACT:
Particles having a tap density of less than 0.4 g/cm3include a hydrophobic amino acid or salt thereof and a therapeutic, prophylactic or diagnostic agent or any combination thereof. Preferred particles include a phospholipid, have a median geometric diameter between about 5 and about 30 microns and an aerodynamic diameter between about 1 and about 5 microns. The particles can be formed by spray-drying and are useful for delivery to the pulmonary system.

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