Use of serotonergic compound for a method of treatment of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S253010

Reexamination Certificate

active

07396854

ABSTRACT:
The present invention relates to a method of treatment of hot flushes with a 5-HT2Creceptor agonist and in particular to the use of the selective 5-HT2Creceptor agonists 1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine and (S)-(+)-3-[(2,3-dihydro-5-methoxy-1H-inden-4-yl)oxy-pyrrolidine or pharmaceutically acceptable acid addition salts thereof for the manufacture of a pharmaceutical formulation adapted for the treatment of hot flushes.

REFERENCES:
patent: 4971969 (1990-11-01), Carlier et al.
patent: 6498184 (2002-12-01), Berendsen
patent: 6987124 (2006-01-01), Berendsen
patent: 0370560 (1990-05-01), None
patent: 0863136 (1998-09-01), None
patent: 0943329 (1999-09-01), None
patent: WO 99/43647 (1999-09-01), None
Berendsen, H. H.: “The Role of Serotonin in Hot Flushes”, Maturitas, (2000) 36 (3) 155-64, Abstract, pp.159-160.
Loprinzi et al: “Preliminary Data from a Randomized Evaluation of Fluoxetine (Prozac) for Treating Hot Flashes in Breast Cancer Survivors”, Breast Cancer Research Treatment, vol. 57, No. 1, 1999, p. 34, Abstract Only.
Goodnick et al: “Selective Serotonin Reuptake Inhibitors in Affective Disorders -I. Basic Pharmacology”, Journal of Psychopharmacology, vol. 12, No. 3, 1998, pp. S5-S20.
Jenck et al: “Antiaversive Effects of 5HT2CReceptor Agonists and Fluoxetine in a Model of Panic-Like Anxiety in Rats”, European Neuropsychopharmacology, vol. 8, No. 3 (1998), pp. 161-168.
Trott, M. D. et al: “An Open Trial of Sertraline for Menopausal Hot Flushes: Potential Involvement of Serotonin in Vasomotor Instability” Delaware Medical Journal, US, Wilmington, DE, vol. 69, No. 9, Sep. 1997, pp. 481-482..

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of serotonergic compound for a method of treatment of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of serotonergic compound for a method of treatment of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of serotonergic compound for a method of treatment of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2806590

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.