Use of selenium for treating patients suffering from...

Details Use of selenium for treating patients suffering from... Use of selenium for treating patients suffering from...

2005-01-18

2005-01-18

Pak, John (Department: 1616)

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Selenium or compound thereof

C424S093510, C424S630000, C424S631000, C424S632000, C424S633000, C424S634000, C424S635000, C424S637000, C424S638000, C424S641000, C424S642000, C424S643000, C424S649000, C424SDIG006, C514S184000, C514S458000, C514S474000, C514S494000, C514S495000, C514S499000, C514S500000, C514S554000, C514S556000, C514S561000, C514S562000, C514S563000, C514S564000, C514S673000, C514S706000, C514S825000, C514S826000, C514S885000, C514S888000, C514S898000, C514S921000

Reexamination Certificate

active

06844012

ABSTRACT:
The invention concerns the use of at least a molecule containing selenium, in an amount corresponding to a daily dose of about 2 to 40 mg, even 80 mg of atomic selenium equivalent, on its own or combined with other synergetic molecules for controlling oxidative stress and excessive inflammatory reaction: zinc, vitamin E, vitamin C, iron binder, glutathione precursor, copper and/or copper input binder, for preparing a medicine for treating severe systemic inflammatory response syndrome, in particular any acute infectious condition endangering the patient's life whether of bacterial, parasitic, fungal or viral origin, and any condition corresponding to a severe onset of inflammatory pathology bringing about an exacerbation of cytokine secretion. The invention is applicable in human and veterinary medicine.

REFERENCES:
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Chemical Abstracts 108:149240 (Apr. 1988).*
Chemical Abstracts 127:171274 (Sep. 1997).*
Chemical Abstracts 129:134509 (Sep. 1998).*
Medline Abstract, accession No. 89032644 (1988).*
T. Zimmerman et al., “Selensubstitution bei Sepsispatienten. Eine prospektiv randomisierte Studie.”, Medizinische Klinik, Sep 15, 1997, 92 Suppl 3 P3-4.
R. Gartner et al., “Selensubstitution bei Sepsispatienten” Medizinische Klinik, 92/Suppl. 3 (12-14).
J. Borner et al., “Selensubstitution bei schweren entzunddlichen chirurgischen Krankheitsbildern sowie Verbrennungen und Verbruhungen im Kindesalter.” Medizinische Klinik, Sep 15, 1997, 92 Suppl 3 P17-9.

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